Bill A
Ups J Med Sci. 1979;84(2):129-36. doi: 10.3109/03009737909179148.
Determinations were made of the 2-hour 22Na space and the 1 and 2 hour 51Cr EDTA spaces in a number of tissues. In regions where the two 51Cr-EDTA spaces were similar and smaller than or similar to the 22Na space the former spaces were regarded as measures of the extra-cellular volume. Using previously published data for plasma volumes, extravascular plasma-equivalent albumin and IgG spaces and the turnover rate constants for the extravascular proteins, it was possible to calculate extravascular protein concentrations and rates of net filtration from the capillaries or lymph flow in some tissues. The albumin concentrations, probably underestimated, were about 40% of the plasma concentrations in small intestine, lung and skeletal muscle, higher in heart muscle and lower in stomach wall. The net filtration or lymph flow, probably overestimated, was 0.81, 1.5, 0.53, 0.61 and 0.12 microliters/min per g in heart muscle, small intestine, lung, stomach wall and skeletal muscle, respectively.
对多种组织中的2小时22Na空间以及1小时和2小时51Cr - EDTA空间进行了测定。在两个51Cr - EDTA空间相似且小于或类似于22Na空间的区域，前者被视为细胞外容积的度量。利用先前发表的关于血浆容积、血管外血浆等效白蛋白和IgG空间以及血管外蛋白质周转速率常数的数据，有可能计算出一些组织中血管外蛋白质浓度以及从毛细血管或淋巴流动的净滤过率。白蛋白浓度可能被低估了，在小肠、肺和骨骼肌中约为血浆浓度的40%，在心肌中较高，在胃壁中较低。净滤过或淋巴流动可能被高估了，在心肌、小肠、肺、胃壁和骨骼肌中分别为每分钟每克0.81、1.5、0.53、0.61和0.12微升。
