Reaction to cold of patients with coronary insufficiency.

Twenty six patients with angina pectoris and coronary insufficiency as judged by an exercise ECG test were examined. About half of the patients had more pronounced ECG changes in a cold room at -15 degrees C than at room temperature. They worked less, their subjective rating of exertion during exercise was higher and the heart performed less work, expressed as the heart rate blood pressure product. The other half of the patients was not much influenced by cold. During an exercise test in the supine position almost all patients got more pronounced ECG changes, worked less and the heart performed less work than in the sitting position. It is suggested that cold exposure as well as a supine body position may to a considerable part exert their effect, i.e. lower the anginal threshold and increase ECG changes, by increasing the central blood volume and the diastolic volume of the left heart and thus ceteres paribus the myocardial oxygen consumption.