Studies on the effects of paraquat and diquat on cells in culture. Viability of macrophages and fibroblasts incubated with paraquat and diquat.
作者信息
Styles J A
出版信息
Br J Exp Pathol. 1974 Feb;55(1):71-7.
Abstract
Paraquat and diquat are of similar toxicity to rat alveolar and peritoneal macrophages in tissue culture. Irreversible damage to macrophages occurs after exposure of 30 min to paraquat or diquat at concentrations as low as 10 mol/l, resulting in the uptake of vital dye. Paraquat and diquat at concentrations of 10 mol/l or less do not reduce viability of fibroblasts as measured by dye exclusion but reduce cloning efficiency. The toxicity of diquat to fibroblasts is approximately ten-fold greater than that of paraquat.
摘要
相似文献
1
Studies on the effects of paraquat and diquat on cells in culture. Viability of macrophages and fibroblasts incubated with paraquat and diquat.
Br J Exp Pathol. 1974 Feb;55(1):71-7.
2
Bipyridylium herbicide toxicity: effects of paraquat and diquat on isolated rat hepatocytes.联吡啶类除草剂毒性：百草枯和敌草快对离体大鼠肝细胞的影响。
J Environ Pathol Toxicol Oncol. 1987 Jan-Feb;7(3):73-84.
3
Correlation of paraquat toxicity with tissue concentrations and weight loss of the rat.百草枯毒性与大鼠组织浓度及体重减轻的相关性。
Toxicol Appl Pharmacol. 1972 Jun;22(2):241-51. doi: 10.1016/0041-008x(72)90174-3.
4
[Paraquat and diquat: mechanisms of toxicity].[百草枯和敌草快：毒性机制]
Acta Med Port. 1989 Jan-Feb;2(1):35-9.
5
A comparative study on the effects of paraquat and diquat on cultured human cells.百草枯和敌草快对培养的人类细胞影响的比较研究
J Toxicol Sci. 1981 Aug;6(3):203-7. doi: 10.2131/jts.6.203.
6
Toxicities of paraquat and diquat herbicides to freshwater copepods (Diaptomus sp. and Eucyclops sp.).
Bull Environ Contam Toxicol. 1980 Dec;25(6):918-20. doi: 10.1007/BF01985631.
7
The toxic effect of diquat on the rat lung after intratracheal administration.
Toxicol Lett. 1986 Jan;30(1):7-12. doi: 10.1016/0378-4274(86)90172-4.
8
The composition of lung lipids after poisoning with paraquat.百草枯中毒后肺脂质的组成。
Br J Exp Pathol. 1970 Dec;51(6):604-10.
9
The effect of high concentrations of oxygen on paraquat and diquat toxicity in rats.高浓度氧气对大鼠百草枯和敌草快毒性的影响。
Arch Toxicol Suppl. 1980;4:415-8. doi: 10.1007/978-3-642-67729-8_95.
10
Influence of bipyridylium compounds on microsomal mixed-function oxidation activities.联吡啶化合物对微粒体混合功能氧化活性的影响。
J Biochem Toxicol. 1988 Fall;3:173-89. doi: 10.1002/jbt.2570030305.
引用本文的文献
1
Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells.百草枯通过线粒体依赖途径诱导RAW264.7细胞凋亡。
Biomol Ther (Seoul). 2015 Sep;23(5):407-13. doi: 10.4062/biomolther.2015.075. Epub 2015 Sep 1.
本文引用的文献
1
The multiplication of tubercle bacilli within normal phagocytes in tissue culture.结核杆菌在组织培养中的正常吞噬细胞内的增殖。
J Exp Med. 1952 Aug;96(2):137-50. doi: 10.1084/jem.96.2.137.
2
Determination of cell viability.细胞活力的测定。
Proc Soc Exp Biol Med. 1958 May;98(1):188-92. doi: 10.3181/00379727-98-23985.
3
The submerged culture of mammalian cells; the spinner culture.哺乳动物细胞的深层培养；转瓶培养。
J Immunol. 1957 Nov;79(5):428-33.
4
Plaque formation and isolation of pure lines with poliomyelitis viruses.脊髓灰质炎病毒的噬斑形成及纯系分离
J Exp Med. 1954 Feb;99(2):167-82. doi: 10.1084/jem.99.2.167.
5
The toxicity of paraquat.百草枯的毒性。
Br J Ind Med. 1966 Apr;23(2):126-32. doi: 10.1136/oem.23.2.126.
6
Mitochondrial increase after long-term feeding of morfamquat.长期喂食吗啉胍后线粒体增加。
Nature. 1969 Oct 4;224(5214):83-4. doi: 10.1038/224083b0.
7
Paraquat and related bipyridyls.百草枯及相关联吡啶类化合物。
Br Med Bull. 1969 Sep;25(3):245-9. doi: 10.1093/oxfordjournals.bmb.a070712.
8
Experimental paraquat poisoning: a histological and electron-optical study of the changes in the lung.实验性百草枯中毒：肺脏变化的组织学和电子光学研究
J Pathol. 1971 Feb;103(2):123-9. doi: 10.1002/path.1711030207.
9
The toxicity of diquat.敌草快的毒性。
Br J Ind Med. 1970 Jan;27(1):51-5. doi: 10.1136/oem.27.1.51.
10
Toxicity of polypropylene in tissue culture.聚丙烯在组织培养中的毒性
Food Cosmet Toxicol. 1969 Sep;7(5):461-72. doi: 10.1016/s0015-6264(69)80426-8.
Zotero 插件