Shternberg E Ia, Druzhinina T A, Kontsevoĭ V A, Molchanova E K
Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(8):1052-7.
A total of 552 patients with attack-like schizophrenia, who attained old age were examined clinically. It was established that the development of negative changes in such patients occurs predominantly during the first half of life. Subsequently not all patients demonstrate a progressive development of the disease and even if it does occur it is seen in the form of more frequent or longer attacks and a complication of psychopathological disorders. At the same time there is a certain correlation between the clinical picture of the attacks and the severity of deficitary changes. A reverse development of some personality changes in long-term remissions in old age are described.
对552例老年期起病的精神分裂症样发作患者进行了临床检查。结果发现,这类患者阴性症状的发展主要发生在生命的前半段。随后,并非所有患者的病情都会呈进行性发展,即使出现病情进展,也表现为发作更频繁或持续时间更长,以及精神病理障碍的并发症。同时,发作的临床表现与缺陷性改变的严重程度之间存在一定的相关性。文中描述了老年期长期缓解过程中某些人格改变的逆向发展。