Dyckner T, Wester P O
Acta Med Scand. 1979;206(1-2):137-40. doi: 10.1111/j.0954-6820.1979.tb13482.x.
Serum and muscle electrolytes were determined in a case of primary aldosteronism before and after potassium and magnesium infusions as well as spironolactone treatment and following surgery. Repeated potassium infusions resulted in a transient normalization of the muscle potassium (K/m), followed within 3-4 days by a return to the previously low K/m. Magnesium infusions did not give any increase in muscle magnesium (Mg/m). On the contrary, there was a decrease in Mg/m concomitant with a decrease in K/m. Treatment with spironolactone for one month was followed by a normalization of both serum and muscle electrolytes. Following surgery the serum potassium and K/m remained normal, but the serum magnesium (Mg/s) and Mg/m showed a decrease to subnormal values. Despite the initial findings of normal Mg/s and Mg/m as well as excretion of more than 80% of the i.v. magnesium dose, this may indicate that there was a magnesium deficiency in the skeletal pool.
在一例原发性醛固酮增多症患者中，测定了输注钾和镁前后、螺内酯治疗期间以及手术后血清和肌肉中的电解质。反复输注钾导致肌肉钾（K/m）暂时恢复正常，但在3 - 4天内又恢复到之前的低K/m水平。输注镁并未使肌肉镁（Mg/m）增加。相反，Mg/m随着K/m的降低而降低。用螺内酯治疗一个月后，血清和肌肉电解质均恢复正常。手术后，血清钾和K/m保持正常，但血清镁（Mg/s）和Mg/m降至低于正常水平。尽管最初发现Mg/s和Mg/m正常，且静脉注射镁剂量的80%以上被排泄，但这可能表明骨骼池中存在镁缺乏。
