Oberdoerster G, Baumert H P, Hochrainer D, Stoeber W
Am Ind Hyg Assoc J. 1979 Jun;40(6):443-50. doi: 10.1080/15298667991429813.
CdO and CdCl2 aerosols were inhaled by two groups of rats and their subsequent clearance behaviour was studied. The half-life of the long term lung clearance rates was identical for both compounds, namely 67 days. For CdO, an initial faster clearance was observed, whereas the initial clearance of CdCl2 did not differ from its long term clearance rate, resulting in a relatively higher Cd burden of the lung in the CdCl2 study. Cd liver and kidney concentrations were also higher in the CdCl2 study, originating from a high resorption rate duringthe time of the exposure.
两组大鼠吸入了氧化镉和氯化镉气溶胶，并对它们随后的清除行为进行了研究。两种化合物的长期肺部清除率半衰期相同，均为67天。对于氧化镉，观察到初始清除速度较快，而氯化镉的初始清除率与其长期清除率没有差异，导致在氯化镉研究中肺部的镉负担相对较高。在氯化镉研究中，肝脏和肾脏中的镉浓度也较高，这源于暴露期间的高吸收率。
