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本文引用的文献

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Molecular models for the circadian clock. I. The chronon concept.生物钟的分子模型。I. 生物钟时元概念。
J Theor Biol. 1967 May;15(2):240-62. doi: 10.1016/0022-5193(67)90206-8.
2
Clock mutants of Drosophila melanogaster.黑腹果蝇的生物钟突变体。
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3
Isolation of circadian clock mutants of Neurospora crassa.粗糙脉孢菌生物钟突变体的分离。
Genetics. 1973 Dec;75(4):605-13. doi: 10.1093/genetics/75.4.605.

莱茵衣藻生物钟突变体之间的重组体。

Recombinants between clock mutants of Chlamydomonas reinhardi.

作者信息

Bruce V G

出版信息

Genetics. 1974 Jun;77(2):221-30. doi: 10.1093/genetics/77.2.221.

DOI:10.1093/genetics/77.2.221
PMID:4847153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213125/
Abstract

Mutants affecting the period length of the biological clock in Chlamydomonas reinhardi have been isolated and a start has been made on analyzing the genetics of this system. In four mutants, the long period characteristic seems to be controlled by single genes at separate loci. Crosses between single mutants, as well as crosses involving three or four mutant genes, yielded progeny with periods characteristic of the parents as well as recombinant types, including normal period (wild type) and extra-long periods (double, triple and quadruple mutants). It was found that the period lengthening effect is additive; that is, the period of double mutants is lengthened by the sum of the period lengthening of the single mutants.

摘要

已经分离出了影响莱茵衣藻生物钟周期长度的突变体,并开始对该系统的遗传学进行分析。在四个突变体中,长周期特征似乎由位于不同位点的单个基因控制。单个突变体之间的杂交,以及涉及三个或四个突变基因的杂交,产生了具有亲本周期特征的后代以及重组类型,包括正常周期(野生型)和超长周期(双突变体、三突变体和四突变体)。研究发现,周期延长效应是累加的;也就是说,双突变体的周期延长量是单个突变体周期延长量之和。