van Wieringen P M, Monnens L A, Schretlen E D
Arch Dis Child. 1974 Jun;49(6):432-7. doi: 10.1136/adc.49.6.432.
Between January 1965 and December 1970, 212 patients with the haemolytic-uraemic syndrome in the Netherlands were analysed in an epidemiological and clinical study of the disease. The disorder typically occurs in early infancy, in children without antecedent illness. The majority of the patients were younger than 4 years. The incidence of the disease in the Netherlands is increasing. The disease occurs throughout the year but peak incidences were noted during the late spring and early summer. Apart from this seasonal influence there was a geographical clustering. The possible relation of the epidemiological features of the syndrome to a viral aetiology is discussed.
1965年1月至1970年12月期间,对荷兰212例溶血尿毒综合征患者进行了该病的流行病学和临床研究分析。该病症通常发生在婴儿早期,患儿无先前疾病史。大多数患者年龄小于4岁。荷兰该病的发病率正在上升。该病全年均可发生,但在春末和初夏发病率最高。除了这种季节性影响外,还存在地理聚集现象。文中讨论了该综合征流行病学特征与病毒病因之间的可能关系。