Billington R W, Itzhaki R F
Br J Cancer. 1974 Apr;29(4):318-23. doi: 10.1038/bjc.1974.73.
Lymphocytes from patients with chronic lymphocytic leukaemia make large amounts of stable, rapidly labelled high molecular weight RNA, but ribosomal RNA methylation is normal. However, fewer ribosomes are available for protein synthesis than in normal lymphocytes.
慢性淋巴细胞白血病患者的淋巴细胞会产生大量稳定、快速标记的高分子量RNA,但核糖体RNA甲基化正常。然而,与正常淋巴细胞相比,可用于蛋白质合成的核糖体数量较少。