铁蛋白中铁的摄取与释放。晶体核心内的表面效应及交换。
Uptake and release of ferritin iron. Surface effects and exchange within the crystalline core.
作者信息
Hoy T G, Harrison P M, Shabbir M
出版信息
Biochem J. 1974 Jun;139(3):603-7. doi: 10.1042/bj1390603.
Abstract
The uptake and subsequent release of iron by apoferritin and ferritin was studied by using labelled iron ((59)Fe). The experimental results are consistent with predictions arising from a model system developed in the interpretation of previous experiments. In this model, uptake and release of ferritin iron is controlled by the available surface area of the small crystalline particles of hydrous ferric oxide found within the ferritin molecule. Evidence is also presented for the exchange of Fe(3+) ions among the various cation sites within these crystallites.
摘要
通过使用放射性铁（⁵⁹Fe）研究了脱铁铁蛋白和铁蛋白对铁的摄取及随后的释放。实验结果与先前实验解释中所建立的模型系统的预测一致。在该模型中，铁蛋白中铁的摄取和释放由铁蛋白分子内发现的水合氧化铁小结晶颗粒的可用表面积控制。还提供了关于这些微晶内各种阳离子位点之间Fe(3+)离子交换的证据。
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本文引用的文献
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