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麻疹预防的新方法(作者译)

[New methods on the measles prophylaxis (author's transl)].

作者信息

de Blasi R, Fazio-Gentile G

出版信息

Ann Sclavo. 1979 Mar-Apr;21(2):113-59.

PMID:485597
Abstract

As for the preventive measures used towards patients with a measles infection, the Authors review in particular the new methods of isolation on the basis of the latest acquisitions on the way and period of contagiousness. As for the preventive measures for healthy people, the Authors review in particular the vaccination route. After having considered the principal types of vaccine used, they demonstrate the efficiency and harmlesness of the live and attenuated virus vaccine, in general, and in particular the "hyperattenuated" vaccine, reviewing the principal causes of the failure of such a vaccine in some cases. They give an ample documentation of the period of immunity (persistance of HAI antibodies) in the vaccined. Considering the experience of other countries, the Authors suggest that it is time to procede in a large scale vaccination in Italy, underlining the fundamental points (use of live and hyperattenuated vaccine, appropriate storage and care of the vaccine, age of vaccination) to prevent failure and to make more and more efficient this type of vaccination.

摘要

至于针对麻疹感染患者采取的预防措施,作者特别根据关于传染途径和传染期的最新知识,回顾了新的隔离方法。至于针对健康人的预防措施,作者特别回顾了疫苗接种途径。在考虑了所用疫苗的主要类型之后,他们论证了活减毒病毒疫苗总体上,特别是“高度减毒”疫苗的有效性和安全性,同时回顾了这种疫苗在某些情况下失效的主要原因。他们充分记录了接种疫苗者的免疫期(血凝抑制抗体的持续时间)。考虑到其他国家的经验,作者建议意大利是时候进行大规模疫苗接种了,强调了预防疫苗接种失败并提高此类疫苗接种效率的要点(使用活疫苗和高度减毒疫苗、对疫苗进行适当储存和保管、接种疫苗的年龄)。

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