Wiedermann G, Ambrosch F
Wien Klin Wochenschr. 1976 Sep 17;88(17):545-54.
A national study, with participation of 82 paediatricians, was carried out on 9472 children over medium observation periods of between 3.13 and 5.46 years with evaluation of the history of measles, incidence of complications and details of vaccination procedure performed. The protection rate of primary vaccination with live vaccine was 0.89, with split vaccine (3 times) 0.67 and after a combination of split vaccine (3 times) with live vaccine (9 to 12 months later) 0.94. Complications due to measles in unvaccinated children were found in 5.9% of cases. Measles complications after failure of vaccination were found in 2.9% and 2.8% of children vaccinated with live or split vaccine, respectively. No such complications were observed in children vaccinated with a combination of split and live vaccines.
一项有82名儿科医生参与的全国性研究,对9472名儿童进行了为期3.13至5.46年的中期观察,评估了麻疹病史、并发症发生率以及所实施的疫苗接种程序细节。活疫苗初次接种的保护率为0.89,裂解疫苗(3次接种)为0.67,在裂解疫苗(3次接种)与活疫苗联合接种(9至12个月后)后为0.94。未接种疫苗的儿童中,麻疹并发症发生率为5.9%。接种活疫苗或裂解疫苗失败后出现麻疹并发症的儿童分别占2.9%和2.8%。接种裂解疫苗与活疫苗联合疫苗的儿童未观察到此类并发症。