6-巯基嘌呤延迟性细胞毒性反应的生化机制。 - Suppr

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超能文献

A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine.

作者信息

Tidd D M, Paterson A R

出版信息

Cancer Res. 1974 Apr;34(4):738-46.

PMID:4856046

Abstract

摘要

相似文献

A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine.6-巯基嘌呤延迟性细胞毒性反应的生化机制。

Cancer Res. 1974 Apr;34(4):738-46.

Distinction between inhibition of purine nucleotide synthesis and the delayed cytotoxic reaction of 6-mercaptopurine.

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Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in sarcoma 180 cells.6-硫鸟嘌呤与6-（甲硫基）嘌呤核糖核苷在肉瘤180细胞中协同作用的生化机制。

Cancer Res. 1972 Oct;32(10):2034-41.

Delayed cytotoxicity of 6-mercaptopurine is compatible with mitotic death caused by DNA damage due to incorporation of 6-thioguanine into DNA as 6-thioguanine nucleotide.6-巯基嘌呤的延迟细胞毒性与因6-硫鸟嘌呤以6-硫鸟嘌呤核苷酸形式掺入DNA而导致的DNA损伤所引起的有丝分裂死亡相符。

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[Antimetabolites in the therapy of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. I].[抗代谢物在人类急性白血病治疗中的应用。药物作用机制及细胞对药物反应的调节因素。I]

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Deoxythioguanosine and thioguanine.脱氧硫代鸟苷和硫代鸟嘌呤。

Clin Pharmacol Ther. 1973 Nov-Dec;14(6):966-9. doi: 10.1002/cpt1973146966.

Mechanisms of action of 6-thioguanine, 6-mercaptopurine, and 8-azaguanine.6-硫鸟嘌呤、6-巯基嘌呤和8-氮鸟嘌呤的作用机制。

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Effect of methotrexate on deoxyribonucleotide pools and DNA synthesis in human lymphocytic cells.甲氨蝶呤对人淋巴细胞中脱氧核糖核苷酸库及DNA合成的影响。

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[Antimetabolites in the treatment of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. II].

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