• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: evidence for dopaminergic supersensitivity in protracted abstinence.

作者信息

Gianutsos G, Hynes M D, Puri S K, Drawbaugh R B, Lal H

出版信息

Psychopharmacologia. 1974 Jan 9;34(1):37-44. doi: 10.1007/BF00421218.

DOI:10.1007/BF00421218
PMID:4856259
Abstract
摘要

相似文献

1
Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: evidence for dopaminergic supersensitivity in protracted abstinence.阿扑吗啡和黑质纹状体损伤对吗啡戒断期间攻击行为和纹状体多巴胺代谢的影响：长期戒断中多巴胺能超敏反应的证据。
Psychopharmacologia. 1974 Jan 9;34(1):37-44. doi: 10.1007/BF00421218.
2
Morphine-induced striatal dopamine efflux depends on the activity of nigrostriatal dopamine neurones.吗啡诱导的纹状体多巴胺外流取决于黑质纹状体多巴胺神经元的活性。
Nature. 1979 Oct 25;281(5733):686-7. doi: 10.1038/281686a0.
3
Apomorphine-induced inhibition of striatal dopamine release: role of dopaminergic receptors in substantia nigra.阿扑吗啡诱导的纹状体多巴胺释放抑制：黑质中多巴胺能受体的作用。
Brain Res. 1978 Apr 21;145(1):180-4. doi: 10.1016/0006-8993(78)90808-9.
4
Supersensitivity of presynaptic receptors involved in the dopaminergic control of striatal high affinity glutamate uptake after 6-hydroxydopamine lesion of nigrostriatal dopaminergic neurons.黑质纹状体多巴胺能神经元经6-羟基多巴胺损伤后，参与纹状体高亲和力谷氨酸摄取多巴胺能调控的突触前受体超敏反应。
Exp Brain Res. 1988;69(2):424-30. doi: 10.1007/BF00247588.
5
Neurochemical evidence for denervation supersensitivity: the effect of unilateral substantia nigra lesions on apomorphine-induced increases in neostriatal acetylcholine levels.去神经超敏反应的神经化学证据：单侧黑质损伤对阿扑吗啡诱导的新纹状体乙酰胆碱水平升高的影响。
Life Sci. 1974 Jul 1;15(1):57-63. doi: 10.1016/0024-3205(74)90193-3.
6
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?长期吗啡治疗会诱发大鼠脑内多巴胺受体超敏反应吗？
Psychopharmacologia. 1975 Jun 19;42(3):225-9. doi: 10.1007/BF00421260.
7
Evidence for a role of endogenous opioids in the nigrostriatal system: influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity.
Brain Res. 1983 Jun 27;270(1):109-17. doi: 10.1016/0006-8993(83)90796-5.
8
Repeated D1 dopamine receptor agonist administration prevents the development of both D1 and D2 striatal receptor supersensitivity following denervation.重复给予 D1 多巴胺受体激动剂可预防去神经支配后 D1 和 D2 纹状体受体超敏反应的发生。
Synapse. 1992 Mar;10(3):206-16. doi: 10.1002/syn.890100304.
9
Dopaminergic receptor activity in substantia nigra in the mechanisms of autoregulation of striatal dopamine release.黑质中多巴胺能受体活性在纹状体多巴胺释放的自动调节机制中所起的作用。
Adv Biochem Psychopharmacol. 1978;19:363-71.
10
Rotational behaviour induced by theophylline in 6-OHDA nigrostriatal denervated rats is dependent on the supersensitivity of striatal dopaminergic receptors.茶碱在6-羟基多巴胺黑质纹状体去神经大鼠中诱导的旋转行为取决于纹状体多巴胺能受体的超敏反应。
Pharmacol Biochem Behav. 1989 Jul;33(3):609-13. doi: 10.1016/0091-3057(89)90396-1.

引用本文的文献

1
Psychopharmacological treatment of disruptive behavior in youths: systematic review and network meta-analysis.精神药理学治疗青少年破坏性行为：系统评价和网络荟萃分析。
Sci Rep. 2023 Apr 28;13(1):6921. doi: 10.1038/s41598-023-33979-2.
2
Dopamine Supersensitivity: A Novel Hypothesis of Opioid-Induced Neurobiological Mechanisms Underlying Opioid-Stimulant Co-use and Opioid Relapse.多巴胺超敏反应：阿片类药物与兴奋剂共同使用及阿片类药物复吸背后阿片类药物诱导神经生物学机制的新假说
Front Psychiatry. 2022 Apr 15;13:835816. doi: 10.3389/fpsyt.2022.835816. eCollection 2022.
3
The role of mesocorticolimbic dopamine in regulating interactions between drugs of abuse and social behavior.

本文引用的文献

1
DEMONSTRATION AND MAPPING OUT OF NIGRO-NEOSTRIATAL DOPAMINE NEURONS.黑质-新纹状体多巴胺能神经元的显示与定位
Life Sci (1962). 1964 Jun;3:523-30. doi: 10.1016/0024-3205(64)90161-4.
2
TOLERANCE TO AND PHYSICAL DEPENDENCE ON MORPHINE IN RATS.大鼠对吗啡的耐受性及身体依赖性
Psychopharmacologia. 1963 May 21;4:247-60. doi: 10.1007/BF00408180.
3
A fluorimetric method for the determination of dopamine (3-hydroxytyramine).一种测定多巴胺（3-羟基酪胺）的荧光分析法。
中脑边缘多巴胺在调节滥用药物与社会行为相互作用中的作用。
Neurosci Biobehav Rev. 2011 Jan;35(3):498-515. doi: 10.1016/j.neubiorev.2010.06.004. Epub 2010 Jun 23.
4
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.利苏瑞ide对大鼠吗啡戒断症状的影响：一种拟多巴胺效应。 （注：原文中“lisuride”可能拼写有误，常见的是“lisuride”，可根据实际情况调整）
Psychopharmacology (Berl). 1982;78(4):326-30. doi: 10.1007/BF00433735.
5
Evidence of a preferential role of brain serotonin in the mechanisms leading to naloxone-precipitated compulsive jumping in morphine-dependent rats.脑血清素在吗啡依赖大鼠中导致纳洛酮诱发强迫性跳跃的机制中起优先作用的证据。
Psychopharmacology (Berl). 1981;74(3):271-4. doi: 10.1007/BF00427109.
6
Morphine dependence and dopaminergic activity: tests of circling responses in rats with unilateral nigral lesions.吗啡依赖与多巴胺能活性：对单侧黑质损伤大鼠的转圈反应测试
Br J Pharmacol. 1980 Dec;70(4):545-54. doi: 10.1111/j.1476-5381.1980.tb09773.x.
7
The effect of melanotrophin release inhibiting factor (MIF) and cyclo (Leu-Gly) on the tolerance to morphine-induced antinociception in the rat: a dose-response study.促黑素释放抑制因子（MIF）和环（亮氨酸-甘氨酸）对大鼠吗啡诱导的抗伤害感受耐受性的影响：一项剂量反应研究。
Br J Pharmacol. 1981 Apr;72(4):707-14. doi: 10.1111/j.1476-5381.1981.tb09152.x.
8
Reduced threshold to pain induced aggression specifically related to morphine dependence.对疼痛诱导攻击的阈值降低，这与吗啡依赖有特定关联。
Psychopharmacologia. 1974 Feb 27;35(3):237-41. doi: 10.1007/BF00437752.
9
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.儿茶酚胺能机制在大鼠吗啡戒断综合征表达中的作用
Psychopharmacologia. 1974;39(2):121-43. doi: 10.1007/BF00440843.
10
Tolerance to the behavioral and neurochemical effects of haloperidol and morphine in rats chronically treated with morphine or haloperidol.长期接受吗啡或氟哌啶醇治疗的大鼠对氟哌啶醇和吗啡行为及神经化学作用的耐受性。
Naunyn Schmiedebergs Arch Pharmacol. 1974;282(2):155-70. doi: 10.1007/BF00499030.
Acta Physiol Scand. 1958 Dec 15;44(3-4):293-8. doi: 10.1111/j.1748-1716.1958.tb01628.x.
4
Relation between the action of dopamine and apomorphine and their O-methylated derivatives upon the CNS.多巴胺和阿扑吗啡及其O-甲基化衍生物对中枢神经系统的作用之间的关系。
Psychopharmacologia. 1965 May 21;7(6):391-9. doi: 10.1007/BF00402361.
5
Classical conditioning of a morphine abstinence phenomenon, reinforcement of opioid-drinking behavior and "relapse" in morphine-addicted rats.吗啡戒断现象的经典条件作用、阿片类药物饮用行为的强化以及吗啡成瘾大鼠的“复吸”
Psychopharmacologia. 1967;10(3):255-84. doi: 10.1007/BF00401386.
6
Procedure for the simultaneous determination of dopamine, 3-methoxy-4-hydroxyphenylacetic acid, and 3,4-dihydroxyphenylacetic acid in brain.
Anal Biochem. 1971 Jul;42(1):113-8. doi: 10.1016/0003-2697(71)90016-9.
7
Physiological parameters of morphine dependence in man--tolerance, early abstinence, protracted abstinence.人体吗啡依赖的生理参数——耐受性、早期戒断、稽延性戒断。
J Psychiatr Res. 1969 Oct;7(1):9-17. doi: 10.1016/0022-3956(69)90007-7.
8
Morphine-withdrawal aggression: sensitization by amphetamines.吗啡戒断性攻击行为：苯丙胺类药物所致的敏化作用
Psychopharmacologia. 1971;22(3):217-23. doi: 10.1007/BF00401783.
9
EEG correlates of morphine challenge in post-addict rats.
Psychopharmacologia. 1971;22(1):56-63. doi: 10.1007/BF00401467.
10
Some implications of conditioning theory for problems of drug abuse.条件作用理论对药物滥用问题的一些启示。
Behav Sci. 1971 Jan;16(1):92-7. doi: 10.1002/bs.3830160108.