Czaplicki M, Bablok L, Janczewski Z
Arch Androl. 1979;3(1):51-5. doi: 10.3109/01485017908985048.
The results of surgical treatment of 33 men with azoospermia and varicocele are presented. Microscopic examination of a testicular biospy revealed the Sertoli-cells-only syndrome in nine subjects while degenerative changes in the seminiferous tubules of one or both testes were present in another six persons. In 15 cases decreased spermatogenesis was noted in the testis on the side ipsilateral to the varicocele. In the remaining three subjects the biopsy revealed active spermatogenesis but with absent spermiogenesis. In all cases the changes were equal or more advanced on the affected side. Improvement of the spermiogram was noted in 12 men (34%) and spermatozoa appeared in the ejaculate within 2 to 14 months after operation. In three spouses four gestations occurred. Only in one case where the spermiogram showed improvement were the degenerative changes present in both testes. In the remainder of subjects demonstrating improvement in semen quality, irreversible changes were absent in at least one testis.
本文介绍了33例无精子症合并精索静脉曲张男性患者的手术治疗结果。对睾丸活检进行显微镜检查发现，9例患者存在唯支持细胞综合征，另有6例患者一侧或双侧睾丸的生精小管出现退行性改变。15例患者精索静脉曲张同侧睾丸的精子发生减少。其余3例患者活检显示有活跃的精子发生，但无精子形成。所有病例中，患侧的改变相同或更严重。12名男性（34%）的精子图谱有所改善，术后2至14个月射精中出现了精子。3对配偶中有4次妊娠。仅在1例精子图谱显示改善的病例中，双侧睾丸均存在退行性改变。在其余精液质量有所改善的患者中，至少一侧睾丸不存在不可逆改变。
