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喂食多不饱和反刍动物源食物的小鼠的生长、繁殖能力和寿命。

Growth, reproductive productivity and longevity of mice fed polyunsaturated ruminant-derived foodstuffs.

作者信息

Fogerty A C, Pennycuik P R, Ferris M C, Baxter R I, Johnson A R

出版信息

Aust J Biol Sci. 1979 Feb;32(1):1-13.

PMID:485972
Abstract

The effects on the well-being of mice of feeding linoleic acid-enriched foodstuffs derived from ruminants receiving protected polyunsaturated oil were determined. Growth, reproductive productivity and longevity were compared in mice fed freeze-dried human diets containing either these products or the corresponding conventional ruminant-derived foods. A laboratory mouse pellet diet was used as a standard for the comparison. Growth rates and life spans were found to be similar in all three groups. Although the reproductive productivity of the mice on the polyunsaturated diet was never significantly different from that of mice on the conventional human diet, productivities of both groups on human diets were usually significantly below those of mice eating pellets. By the third generation of the second reproduction study, productivities of both these groups of mice had returned to the same level as those of mice eating pellets. Possible reasons for the depression in reproductive productivity in mice on the human diets are discussed. It was concluded that the polyunsaturated human diet neither impaired nor improved the lives of the animals eating the diet relative to the lives of animals eating the conventional human diet.

摘要

研究了给食用经保护的多不饱和油的反刍动物所产富含亚油酸的食物对小鼠健康的影响。比较了喂食含有这些产品或相应传统反刍动物源食物的冻干人类饮食的小鼠的生长、繁殖生产力和寿命。使用实验室小鼠颗粒饲料作为比较标准。发现三组小鼠的生长速率和寿命相似。尽管食用多不饱和饮食的小鼠的繁殖生产力与食用传统人类饮食的小鼠的繁殖生产力从未有显著差异,但两组食用人类饮食的小鼠的生产力通常显著低于食用颗粒饲料的小鼠。在第二代繁殖研究的第三代中,这两组小鼠的生产力都恢复到了与食用颗粒饲料的小鼠相同的水平。讨论了食用人类饮食的小鼠繁殖生产力下降的可能原因。得出的结论是,相对于食用传统人类饮食的动物的生活,多不饱和人类饮食既没有损害也没有改善食用该饮食的动物的生活。

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