Jooste P L, Wolfswinkel J M, Schoeman J J, Strydom N B
Aviat Space Environ Med. 1979 Jul;50(7):734-5.
Immediately following 4 h of continuous exercise at +/- 45% Vo2max in heat, a 23-year-old, well-trained man displayed epileptic-type convulsions. One week preceeding this incident, he completed an identical work test successfully under room temperature conditions. An assessment of his physiological and biochemical results indicated only one abnormality: during exercise in heat, an abnormally low serum magnesium concentration prevailed for most of the test. Treatment with phenobarb and magnesium chloride enteric tablets ("Slow Mag", 2 x 535 mg/d) reversed the biochemical abnormality. After checking his resting serum magnesium, the subject subsequently heat acclimatized and repeated similar treadmill tests as before without any ill effects.
在高温环境下以±45%最大摄氧量进行4小时持续运动后，一名23岁、训练有素的男性立即出现癫痫样惊厥。在此次事件发生前一周，他在室温条件下成功完成了相同的工作测试。对他的生理和生化结果进行评估后发现只有一项异常：在高温环境下运动时，大部分测试时间内血清镁浓度异常低。用苯巴比妥和氯化镁肠溶片（“缓释镁”，2×535毫克/天）治疗可纠正生化异常。在检查了他的静息血清镁水平后，该受试者随后进行了热适应，并重复了之前的类似跑步机测试，未出现任何不良影响。
