Snyder S H, Faillace L, Hollister L
Science. 1967 Nov 3;158(3801):669-70. doi: 10.1126/science.158.3801.669.
We have assessed the effects in normal control volunteers of 2,5-dimethoxy-4-methyl-amphetamine, the chemical present in the hallucinogenic drug STP, in two independent trials. In low doses, this compound produces a mild euphoria. Doses greater than 3 milligrams may cause pronounced hallucinogenic effects lasting about 8 hours and similar to those produced by hallucinogenic doses of lysergic acid diethylamide, mescaline, and psilocybin. 2,5-Dimethoxy-4-methyl-amphetamine, which is chemically related to mescaline and amphetamine, is about 100 times more potent as a hallucinogen than mescaline and only one-thirtieth as potent as lysergic acid diethylamide. Its psychological effects are not accentuated by chlorpromazine.
我们在两项独立试验中评估了致幻药物STP中的化学物质2,5-二甲氧基-4-甲基苯丙胺对正常对照志愿者的影响。低剂量时，这种化合物会产生轻微的欣快感。剂量大于3毫克可能会导致明显的致幻效果，持续约8小时，类似于致幻剂量的麦角酸二乙酰胺、三甲氧苯乙胺和裸盖菇素所产生的效果。2,5-二甲氧基-4-甲基苯丙胺在化学上与三甲氧苯乙胺和苯丙胺有关，作为致幻剂，其效力比三甲氧苯乙胺强约100倍，仅为麦角酸二乙酰胺效力的三十分之一。氯丙嗪不会增强其心理效应。
