Moore M A, Owen J J
J Exp Med. 1967 Oct 1;126(4):715-26. doi: 10.1084/jem.126.4.715.
Experiments utilizing chromosome marker and histological techniques in combination with parabiosis and transplanatation procedures have demonstrated an inflow of blood-home stem cells into the chick embryo thymic rudiment. There is close similarity between the histological picture in the chick and in the mouse thymic rudiment, and it is proposed that a similar developmental process takes place in both. It may be concluded that the epithelial component of the thymic rudiment, rather than producing lymphoid cells itself, furnishes an inductive environment for the proliferation and differentiation of stem cells derived extrinsically.
利用染色体标记和组织学技术，结合联体生活和移植程序进行的实验表明，造血干细胞流入鸡胚胸腺原基。鸡和小鼠胸腺原基的组织学图像非常相似，因此有人提出两者都发生了类似的发育过程。可以得出结论，胸腺原基的上皮成分本身并不产生淋巴细胞，而是为源自外部的干细胞的增殖和分化提供诱导环境。
