淋巴细胞性脉络丛脑膜炎：“耐受”感染小鼠产生抗体
Lymphocytic choriomeningitis: production of antibody by "tolerant" infected mice.
作者信息
Oldstone M B, Dixon F J
出版信息
Science. 1967 Dec 1;158(3805):1193-5. doi: 10.1126/science.158.3805.1193.
PMID:4862090
Abstract
Newborn mice infected with lymphocytic choriomeningitis virus are not immunologically tolerant to the agent but, rather, appear to make antibody to the virus. This antibody was detectable only in the kidneys, where presumably it had been deposited in the glomeruli in the form of complexes of antibody, virus, and complement.
摘要
感染淋巴细胞性脉络丛脑膜炎病毒的新生小鼠对该病原体并无免疫耐受性，相反，它们似乎会产生针对该病毒的抗体。这种抗体仅在肾脏中可检测到，推测它是以抗体、病毒和补体复合物的形式沉积在肾小球中。
Zotero 插件