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鼠类微孢子虫在瑞士小鼠中的实验性传播

Experimental transmission of a murine microsporidian in Swiss mice.

作者信息

Nelson J B

出版信息

J Bacteriol. 1967 Nov;94(5):1340-5. doi: 10.1128/jb.94.5.1340-1345.1967.

DOI:10.1128/jb.94.5.1340-1345.1967
PMID:4862191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC276830/
Abstract

The production of ascitic fluid and splenomegaly on intraperitoneal injection in weanlings was used as a test for microsporidia after introduction by other routes and in other loci. Oral and cerebral administration was followed only by enlarged spleens which reproduced the ascitic response on passage. Microsporidia were demonstrable by phase microscopy in all fluids. Positive findings were also obtained with liver, kidney, brain, lungs, blood, and urine. Intramuscular and intranasal injection were occasionally followed by ascites, but splenomegaly again predominated. The results of contact experiments indicated that the organisms were not readily communicable either in weanlings or nurslings. Relation of the microsporidian to Encephalitozoon cuniculi (Nosema cuniculi Lainson et al.) is discussed.

摘要

在断奶仔猪经其他途径和在其他部位接种后,通过腹腔注射产生腹水和脾肿大作为微孢子虫的一项检测。口服和脑内给药后仅出现脾脏肿大,传代时再现腹水反应。通过相差显微镜在所有液体中均可检测到微孢子虫。在肝脏、肾脏、脑、肺、血液和尿液中也获得了阳性结果。肌肉注射和鼻内注射偶尔会导致腹水,但脾肿大再次占主导。接触实验结果表明,这些生物体在断奶仔猪或哺乳仔猪中不易传播。讨论了微孢子虫与兔脑原虫(兔鼻疽原虫Lainson等人)的关系。

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Experimental transmission of a murine microsporidian in Swiss mice.鼠类微孢子虫在瑞士小鼠中的实验性传播
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Encephalitozoonosis (nosematosis) causing bilateral cataract in a rabbit.兔脑胞内原虫病(鼻疽病)导致双侧白内障。
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本文引用的文献

1
NOSEMA MURIS N. SP., A NEW MICROSPORIDIAN PARASITE OF THE WHITE MOUSE (MUS MUSCULUS L.).鼠鼻孢菌新种,小白鼠(小家鼠)的一种新的微孢子虫寄生虫
J Protozool. 1965 Feb;12:78-83. doi: 10.1111/j.1550-7408.1965.tb01816.x.
2
NOSEMATOSIS, A MICROSPORIDIAL INFECTION OF RODENTS AND OTHER ANIMALS, INCLUDING MAN.鼻孢子虫病,一种由微孢子虫引起的感染,可感染啮齿动物和包括人类在内的其他动物。
Br Med J. 1964 Aug 22;2(5407):470-2. doi: 10.1136/bmj.2.5407.470.
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Occult endemic encephalitozoonosis of the central nervous system of mice (Swiss-Bagg-O'Grady strain).小鼠(瑞士-巴格-奥格雷迪品系)中枢神经系统隐匿性地方性脑胞内原虫病
J Neuropathol Exp Neurol. 1962 Oct;21:519-33. doi: 10.1097/00005072-196210000-00002.
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A case of Encephalitozoon-like body infection in man.一例人类似脑炎微孢子虫体感染病例。
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Ascites and hepatosplenomegaly in mice associated with protozoan-like cytoplasmic structures.
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