水疱液中的酸性水解酶。7. 二甲基亚砜和热的影响。

Acid hydrolases in blister fluid. 7. Influence of dimethyl sulphoxide and heat.

作者信息

Volden G

出版信息

Br J Dermatol. 1979 Aug;101(2):155-7. doi: 10.1111/j.1365-2133.1979.tb05600.x.

DOI:10.1111/j.1365-2133.1979.tb05600.x

Abstract

Increased acid hydrolase activity has been demonstrated in suction blister fluid 1.5 h after the application of established lysosomal labilizing agents. Both the pattern of enzyme activity and the magnitude of the increases were similar to those following cutaneous inflammation. These data confirm our previous observations that acid hydrolases do indeed play a role in cutaneous inflammation, but their release is not the initial event in this process.

摘要

在应用已确定的溶酶体不稳定剂1.5小时后，抽吸水疱液中的酸性水解酶活性增加。酶活性模式和增加幅度均与皮肤炎症后的情况相似。这些数据证实了我们之前的观察结果，即酸性水解酶确实在皮肤炎症中起作用，但它们的释放并非该过程中的初始事件。