大肠杆菌K-12的D-丝氨酸脱氨酶系统中显性的“位置效应”
"Position effect" on dominance in the D-serine deaminase system of Escherichia coli K-12.
作者信息
McFall E
出版信息
J Bacteriol. 1967 Dec;94(6):1989-93. doi: 10.1128/jb.94.6.1989-1993.1967.
Abstract
A completely stable F32 merodiploid has been isolated, which has the dsd genotype dsdA(+)dsdCx3 /F -dsdA(+)dsdC(+). The stabilization apparently does not result from an alteration in the F, or from its integration in the chromosome, but rather from a chromosomal aberration. The stable strain can exist in two forms, which interconvert at low frequency. In one form, the episomal dsd markers are in normal apposition with the chromosomal markers, and in this case cis dominance of dsdCx3 is incomplete. In the other form, the two regions are not in normal apposition, and dsdCx3 is completely cis dominant. A model to explain these findings is presented.
摘要
已分离出一种完全稳定的F32部分二倍体，其dsd基因型为dsdA(+)dsdCx3 /F -dsdA(+)dsdC(+)。这种稳定性显然不是由F因子的改变或其整合到染色体中导致的，而是由染色体畸变引起的。稳定菌株可以以两种形式存在，它们在低频下相互转换。在一种形式中，附加体dsd标记与染色体标记正常并列，在这种情况下，dsdCx3的顺式显性不完全。在另一种形式中，这两个区域不是正常并列的，并且dsdCx3是完全顺式显性的。本文提出了一个解释这些发现的模型。
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