Tavassoli M, Watson L R, Khademi R
Cell Tissue Res. 1979 Aug;200(2):215-22. doi: 10.1007/BF00236414.
In newborn rats, the marrow cavity of tail vertebrae is hemopoietic and contains no adipose tissue. The latter develops soon after birth to replace the hemopoietic tissue within the nonexpansile volume of the marrow cavity. By transposing the tail into the warmer environment of the abdomen, hemopoiesis was retained, and the development of adipose tissue was prevented in the transposed segment, when the operation was done in preweanling but not in adult animals. Systemic stimuli of erythropoiesis (phlebotomy, induced hemolysis) acted synergistically with the temperature increment to retain hemopoiesis. The findings support the concept that adipose cells in the yellow marrow are relatively stable and once developed, they are not readily mobilized. The findings may also explain the discrepancies in the results obtained by rat tail transposition.
在新生大鼠中，尾椎骨的骨髓腔具有造血功能且不含脂肪组织。出生后不久，脂肪组织开始发育，在骨髓腔容积不变的情况下取代造血组织。将尾巴移至腹部较温暖的环境中，若手术在断奶前而非成年动物中进行，造血功能得以保留，且移植段的脂肪组织发育受到抑制。全身性红细胞生成刺激因素（放血、诱导溶血）与温度升高协同作用以保留造血功能。这些发现支持了黄骨髓中的脂肪细胞相对稳定这一概念，即一旦发育形成，它们就不易被动员。这些发现也可能解释了大鼠尾巴移植所获结果中的差异。
