Wolthuis R A, Froelicher V F, Hopkirk A, Fischer J R, Keiser N
Circulation. 1979 Nov;60(5):1028-35. doi: 10.1161/01.cir.60.5.1028.
Forty asymptomatic male patients at low risk for cardiovascular disease completed maximal treadmill testing. Electrocardiograms from leads CC5, CM5, V5, Yh and Z were recorded across multiple pretest, exercise and recovery conditions. ECG waveforms were subsequently digitized, averaged and processed to provide Q-, R-, S- and T-wave amplitudes, ST-segment means and slopes, and QS- and RT-interval durations. Average R-wave amplitude increased during early exercise and then dramatically decreased to maximum effort. Average S-wave amplitude became greater as exercise progressed. Average J junction was slightly positive before exercise, became negative during exercise (except lead Z) and returned to zero after exercise. The ST-segment slope increased dramatically with progressive exercise. The response of T-wave amplitude, RT and QS intervals are also described. Separately, 22 asymptomatic male subjects each completed two maximal treadmill tests 2 weeks apart. ECG data acquisition and processing were similar to those noted above. Pooled, within-subject estimates of variability were computed for the ECG leads, ECG measurements and protocol conditions. These variability estimates are useful for interpreting ECG responses to exercise testing.
40名心血管疾病低风险的无症状男性患者完成了极限平板运动试验。在多个测试前、运动和恢复条件下记录了CC5、CM5、V5、Yh和Z导联的心电图。随后对心电图波形进行数字化、平均和处理，以提供Q波、R波、S波和T波振幅、ST段均值和斜率以及QS和RT间期持续时间。平均R波振幅在运动早期增加，然后在最大运动强度时急剧下降。随着运动进行，平均S波振幅变大。平均J点在运动前略为正值，运动期间变为负值（Z导联除外），运动后恢复到零。ST段斜率随着运动强度增加而急剧增加。还描述了T波振幅、RT和QS间期的反应。另外，22名无症状男性受试者每人在相隔2周的时间内完成了两次极限平板运动试验。心电图数据采集和处理与上述类似。针对心电图导联、心电图测量和方案条件计算了受试者内合并的变异性估计值。这些变异性估计值有助于解释运动试验的心电图反应。
