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J Bacteriol. 1968 Jun;95(6):2242-8. doi: 10.1128/jb.95.6.2242-2248.1968.
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本文引用的文献

1
LIPID-PHOSPHOACETYLMURAMYL-PENTAPEPTIDE AND LIPID-PHOSPHODISACCHARIDE-PENTAPEPTIDE: PRESUMED MEMBRANE TRANSPORT INTERMEDIATES IN CELL WALL SYNTHESIS.脂质 - 磷酰乙酰胞壁酰 - 五肽和脂质 - 磷酰二糖 - 五肽：细胞壁合成中推测的膜转运中间体
Proc Natl Acad Sci U S A. 1965 Apr;53(4):881-9. doi: 10.1073/pnas.53.4.881.
2
BIOSYNTHESIS OF CELL WALL POLYSACCHARIDE IN MUTANT STRAINS OF SALMONELLA. IV. SYNTHESIS OF S-SPECIFIC SIDE-CHAIN.沙门氏菌突变株中细胞壁多糖的生物合成。IV. S-特异性侧链的合成。
Biochem Biophys Res Commun. 1965 Apr 23;19:322-7. doi: 10.1016/0006-291x(65)90462-6.
3
BIOSYNTHESIS OF BACTERIAL LIPOPOLYSACCHARIDE, IV. ENZYMATIC INCORPORATION OF MANNOSE, RHAMNOSE, AND GALACTOSE IN A MUTANT STRAIN OF SALMONELLA TYPHIMURIUM.细菌脂多糖的生物合成，IV。鼠伤寒沙门氏菌突变株中甘露糖、鼠李糖和半乳糖的酶促掺入。
Proc Natl Acad Sci U S A. 1965 Jan;53(1):207-14. doi: 10.1073/pnas.53.1.207.
4
ENZYMATIC SYNTHESIS OF THE SALMONELLA O-ANTIGEN.沙门氏菌O抗原的酶促合成
Proc Natl Acad Sci U S A. 1964 Nov;52(5):1302-9. doi: 10.1073/pnas.52.5.1302.
5
Biosynthesis of bacterial lipopolysaccharide. I. Enzymatic incorporation of galactose in a mutant strain of Salmonella.细菌脂多糖的生物合成。I. 半乳糖在沙门氏菌突变株中的酶促掺入。
Proc Natl Acad Sci U S A. 1962 Oct 15;48(10):1831-8. doi: 10.1073/pnas.48.10.1831.
6
Biosynthesis of the peptidoglycan of bacterial cell walls. I. Utilization of uridine diphosphate acetylmuramyl pentapeptide and uridine diphosphate acetylglucosamine for peptidoglycan synthesis by particulate enzymes from Staphylococcus aureus and Micrococcus lysodeikticus.细菌细胞壁肽聚糖的生物合成。I. 金黄色葡萄球菌和溶壁微球菌的颗粒酶利用尿苷二磷酸乙酰胞壁酰五肽和尿苷二磷酸乙酰葡糖胺进行肽聚糖合成。
Arch Biochem Biophys. 1966 Sep 26;116(1):487-515. doi: 10.1016/0003-9861(66)90056-7.
7
Biosynthesis of O-antigen in Salmonella typhimurium.
Ann N Y Acad Sci. 1966 Jun 30;133(2):391-404. doi: 10.1111/j.1749-6632.1966.tb52379.x.
8
Biosynthesis of bacterial lipopolysaccharide. V. Lipid-linked intermediates in the biosynthesis of the O-antigen groups of Salmonella typhimurium.细菌脂多糖的生物合成。V. 鼠伤寒沙门氏菌O抗原基团生物合成中的脂质连接中间体。
Proc Natl Acad Sci U S A. 1965 Jul;54(1):228-35. doi: 10.1073/pnas.54.1.228.
9
Structure of a lipid intermediate in cell wall peptidoglycan synthesis: a derivative of a C55 isoprenoid alcohol.细胞壁肽聚糖合成中脂质中间体的结构：一种C55类异戊二烯醇的衍生物。
Proc Natl Acad Sci U S A. 1967 Jun;57(6):1878-84. doi: 10.1073/pnas.57.6.1878.
10
Evidence for an intermediate stage in the biosynthesis of the Salmonella O-antigen.沙门氏菌O抗原生物合成中间阶段的证据。
Proc Natl Acad Sci U S A. 1965 Jul;54(1):235-41. doi: 10.1073/pnas.54.1.235.

柠檬酸杆菌139 O抗原的生物合成

Biosynthesis of the O antigen from Citrobacter 139.

作者信息

Yuan R, Horecker B L

出版信息

J Bacteriol. 1968 Jun;95(6):2242-8. doi: 10.1128/jb.95.6.2242-2248.1968.

DOI:10.1128/jb.95.6.2242-2248.1968
PMID:4876133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC315158/
Abstract

The biosynthesis of the O antigen of Citrobacter 139 (Escherichia coli 3 Zurich 4,5,12:z(20)) was shown to proceed through a series of lipid-linked intermediates, similar to those involved in O-antigen synthesis in Salmonella. Galactose was the first sugar incorporated, followed by rhamnose and mannose. Abequose was incorporated from cytidine diphosphate (CDP)-abequose only when all three of the other nucleotide sugars (uridine diphosphate galactose, guanosine diphosphate mannose, and thymidine diphosphate rhamnose) were present. Rhamnosyl-galactosyl 1-phosphate and mannosyl-rhamnosyl-galactosyl 1-phosphate were identified as the products of mild alkaline hydrolysis of the lipid-linked intermediates.

摘要

已证明柠檬酸杆菌139（大肠杆菌3苏黎世4,5,12:z(20)）的O抗原生物合成过程通过一系列脂质连接中间体进行，这与沙门氏菌中参与O抗原合成的中间体相似。半乳糖是第一个掺入的糖，其次是鼠李糖和甘露糖。仅当其他三种核苷酸糖（尿苷二磷酸半乳糖、鸟苷二磷酸甘露糖和胸苷二磷酸鼠李糖）都存在时，阿比可糖才从胞苷二磷酸（CDP）-阿比可糖掺入。鼠李糖基-半乳糖基1-磷酸和甘露糖基-鼠李糖基-半乳糖基1-磷酸被鉴定为脂质连接中间体温和碱性水解的产物。