Peck V, Shenkman L
Clin Pharmacol Ther. 1979 Oct;26(4):442-4. doi: 10.1002/cpt1979264442.
Several psychotropic drugs have been associated with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). We report here a patient who on two occasions developed clinically significant hyponatremia while receiving the antipsychotic drug, haloperidol. The criteria for the syndrome of inappropriate secretion of ADH were fulfilled and other causes of SIADH were excluded. We documented inability in this patient to excrete a water load while on haloperidol and normal ability in its absence. This case therefore illustrates SIADH due to haloperidol.
几种精神药物与抗利尿激素分泌不当综合征（SIADH）有关。我们在此报告一名患者，该患者在接受抗精神病药物氟哌啶醇治疗期间两次出现具有临床意义的低钠血症。抗利尿激素分泌不当综合征的标准得到满足，且排除了SIADH的其他病因。我们记录到该患者在服用氟哌啶醇时无法排出水负荷，而在未服用时则具有正常能力。因此，该病例说明了氟哌啶醇所致的SIADH。
