Batchelor J F, Follenfant M J, Garland L G, Gorvin J H, Green A F, Hodson H F, Hughes D T, Tateson J E
Lancet. 1975 May 24;1(7917):1169-70. doi: 10.1016/s0140-6736(75)93141-4.
In-vivo studies have demonstrated antiallergic properties in doxantrazole when given orally to rats. These properties were confirmed in work with in-vitro preparations. No significant animal toxicity has been detected. 200 mg. given by mouth inhibited the immediate-type asthmatic response in volunteer patients challenged with specific antigen.
体内研究表明,给大鼠口服多沙唑嗪时具有抗过敏特性。这些特性在体外制剂的研究中得到了证实。未检测到明显的动物毒性。口服200毫克可抑制接受特异性抗原激发的志愿者患者的速发型哮喘反应。