Izquierdo J M, Rougerie J, Lapras C, Sanz F
Childs Brain. 1979;5(6):505-12.
We present the results of a cooperative study of 15 cases of suprasellar dysgerminomas (ectopic pinealomas) and a review of cases of the literature with histological confirmation. In all the cases, histological similarities to the germinomas which appear extracerebrally, particularly testicular seminomas, were observed. We were unable to find in the sellar region tumors of true pineal histology and tend therefore to confirm the germinal origin of these neoplasms. From a clinical point of view, we define a syndrome that these tumors produce, consisting of diabetes insipidus as the first sign, visual impairment and endocrine disturbances, with few or no radiological signs in plain studies.
我们展示了一项关于15例鞍上生殖细胞瘤（异位松果体瘤）的合作研究结果，并对经组织学证实的文献病例进行了回顾。在所有病例中，均观察到与脑外出现的生殖细胞瘤，特别是睾丸精原细胞瘤的组织学相似性。我们在鞍区未发现真正松果体组织学的肿瘤，因此倾向于证实这些肿瘤的生发起源。从临床角度来看，我们定义了这些肿瘤所产生的一种综合征，其首发症状为尿崩症，伴有视力障碍和内分泌紊乱，在平片研究中几乎没有或没有放射学征象。
