Wright D H
J Clin Pathol. 1968 Sep;21(5):643-9. doi: 10.1136/jcp.21.5.643.
Lipid staining, using oil red 0 and Sudan black B stain, was carried out on frozen sections of formalin-fixed tumour tissue from 142 cases of malignant lymphoma. Most cases of Burkitt's tumour contained abundant coarse lipid droplets both within the cytoplasm of the lymphoid cells and within non-neoplastic histiocytes scattered throughout the tumour. Lymphocytic lymphomas contained little stainable fat. Histiocytic and stem-cell lymphomas were almost equally divided between those containing abundant lipid droplets and those devoid of lipid. It is suggested that the demonstration of abundant cytoplasmic lipid droplets may assist in the diagnosis of Burkitt's tumour although this feature is not in itself diagnostic. The significance of the lipid droplets in the cells of Burkitt's tumour is discussed in relation to the histogenesis of the tumour.
采用油红O和苏丹黑B染色法，对142例恶性淋巴瘤福尔马林固定肿瘤组织的冰冻切片进行脂质染色。大多数伯基特瘤病例在淋巴样细胞的胞质内以及散布于肿瘤各处的非肿瘤性组织细胞内均含有丰富的粗大脂质滴。淋巴细胞性淋巴瘤几乎没有可染色的脂肪。组织细胞性和干细胞性淋巴瘤中，含有丰富脂质滴的和不含脂质的病例数几乎相等。有人提出，尽管丰富的胞质脂质滴这一特征本身并非诊断性的，但它可能有助于伯基特瘤的诊断。本文结合肿瘤的组织发生学讨论了伯基特瘤细胞中脂质滴的意义。
