The metabolism of saddamine in man: the fate of the benzylamine moiety of saddamine.

The metabolism of 14C-saddamine radiolabelled in the benzylamine moiety has been investigated in man after oral administration. 14C-Hippuric acid was found to be the only radiolabelled urinary metabolite, the overall amount of which was equivalent to over 95% of the dose. The time taken for elimination of 50% of the dose in the urine was approximately five hours and the corresponding value for 14C-benzylamine hydrochloride was less than one hour.