一个允许中性等位基因电泳迁移率连续变化的模型。
A model allowing continuous variation in electrophoretic mobility of neutral alleles.
作者信息
Cobbs G
出版信息
Genetics. 1979 Jun;92(2):669-78. doi: 10.1093/genetics/92.2.669.
Abstract
The infinite-sites model with no recombination is extended to include mutations that affect electrophoretic mobility. The model allows the effect of a single-site mutation to have a continuous effect on mobility. Formulae are obtained for the variance of electrophoretic mobility of alleles after an arbitrary lenght of time. A special case of the general model is the case of stepwise production of neutral alleles with an arbitrary number of steps.
摘要
无重组的无限位点模型被扩展，以纳入影响电泳迁移率的突变。该模型允许单一位点突变对迁移率产生连续影响。得出了经过任意时长后等位基因电泳迁移率方差的公式。一般模型的一个特殊情况是具有任意步数的中性等位基因逐步产生的情况。
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