在果蝇中通过电泳分离的同工酶内的等位基因异质性。
Allelic heterogeneity within allozymes separated by electrophoresis in Drosophila pseudoobscura.
作者信息
McDowell R E, Prakash S
出版信息
Proc Natl Acad Sci U S A. 1976 Nov;73(11):4150-3. doi: 10.1073/pnas.73.11.4150.
Abstract
Electrophoretic separation of esterase-5 allozymes of Drosophila pseudoobscura in gels of different acrylamide concentrations and in different buffer systems has revealed the existence of six different alleles within the most frequent class, esterase-5(1.00), and three alleles in the other most frequent class, esterase-5(1.07). Two of the alleles affect subunit binding. Esterase-5 allozyme classes based on electrophoresis in 5% acrylamide gels are therefore highly heterogeneous.
摘要
在不同丙烯酰胺浓度的凝胶以及不同缓冲系统中，对拟暗果蝇酯酶-5同工酶进行电泳分离后发现，在最常见的类别酯酶-5(1.00)中存在六个不同的等位基因，在另一个最常见的类别酯酶-5(1.07)中存在三个等位基因。其中两个等位基因影响亚基结合。因此，基于在5%丙烯酰胺凝胶中进行电泳的酯酶-5同工酶类别具有高度的异质性。
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