De Grandi P, Ramzin M, Lüthi A, Hinselmann M
Gynecol Obstet Invest. 1979;10(1):23-31. doi: 10.1159/000299914.
Amylase concentration, L/S ratio and lecithin concentration were measured in 110 samples of amniotic fluid in 106 uneventful pregnancies. Amylase concentrations lower than 200 U/l corresponded significantly (p less than 0.001) to a gestational age less than the 37th week as well as to a L/S ratio lower than 2 and to lecithin concentrations lower than 3.5 mg%. Furthermore, amylase values higher than 300 U/l corresponded significantly (p less than 0.001) to a gestational age over the 37th week as to an L/S ratio over 2 and to lecithin concentrations over 3.5 mg%. On the other hand amylase concentrations ranging between 200 and 300 U/l failed to show any significant relationship neither to the age of gestation nor to the concentration of phospholipids. These findings show that the amylase test is a useful method for prediction of fetal maturity. Since the procedure of determination of the amylase concentration is very simple, cheap and rapid, the test can be used as screening method. However, when amylase concentrations are found to range between 200 and 300 U/l specific tests for assessment of fetal maturity have to be applied.
对106例正常妊娠的110份羊水样本进行了淀粉酶浓度、L/S比值和卵磷脂浓度的检测。淀粉酶浓度低于200U/l与孕周小于37周、L/S比值低于2以及卵磷脂浓度低于3.5mg%显著相关（p<0.001）。此外，淀粉酶值高于300U/l与孕周超过37周、L/S比值高于2以及卵磷脂浓度高于3.5mg%显著相关（p<0.001）。另一方面，淀粉酶浓度在200至300U/l之间与孕周或磷脂浓度均无显著关系。这些发现表明，淀粉酶检测是预测胎儿成熟度的一种有用方法。由于淀粉酶浓度的测定方法非常简单、廉价且快速，该检测可作为筛查方法。然而，当发现淀粉酶浓度在200至300U/l之间时，必须应用评估胎儿成熟度的特定检测方法。
