Lazarević B, Poljaković L, Ljubić A, Radunović N
Jugosl Ginekol Perinatol. 1989 Sep-Dec;29(5-6):165-7.
A prospective study involved 90 patients divided into groups of high risk and risk pregnancies, which matched in age, parity and gestational age. Two methods for the amniotic fluid phospholipid analysis were compared. The value of lecithin was measured by the two phase UV enzyme method and the lecithin/sphingomyelin (L/S) ratio was determined by Gluck's method. The correlation of lecithin and the L/S ratio with gestational age did not prove statistically significant. No correlation was found between the lecithin concentration and L/S ratio on the one hand and the occurrence of the respiratory distress syndrome on the other. The increase of RDS in high risk pregnancies was not statistically significant. The lecithin concentration determination appeared to be a more specific method (37%) than the L/S ratio (19%), and the predictive value of the negative test also proved to be higher (94%) in relation to the L/S ratio (89%).
一项前瞻性研究涉及90名患者，这些患者被分为高危妊娠组和风险妊娠组，两组在年龄、产次和孕周方面相匹配。比较了两种羊水磷脂分析方法。卵磷脂值采用双相紫外酶法测量，卵磷脂/鞘磷脂（L/S）比值采用格鲁克法测定。卵磷脂和L/S比值与孕周之间的相关性未被证明具有统计学意义。一方面，卵磷脂浓度和L/S比值与另一方面呼吸窘迫综合征的发生之间未发现相关性。高危妊娠中呼吸窘迫综合征的增加没有统计学意义。卵磷脂浓度测定似乎是一种比L/S比值更具特异性的方法（37%对19%），并且阴性试验的预测价值相对于L/S比值（89%）也更高（94%）。
