Multicompartment pharmacokinetic analysis and simulations using a programmable calculator.
作者信息
Niazi S
出版信息
Int J Biomed Comput. 1979 May;10(3):245-55. doi: 10.1016/0020-7101(79)90015-1.
PMID:489156
Abstract
This paper describes the use of a programmable calculator (HP-97), for fitting plasma concentration profiles to 1 and 2 compartment open models and calculating fitted and derived parameters together with estimates of steady state plasma drug levels following various dosage regimens in clinical settings.
摘要
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