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Multicompartment pharmacokinetic analysis and simulations using a programmable calculator.

作者信息

Niazi S

出版信息

Int J Biomed Comput. 1979 May;10(3):245-55. doi: 10.1016/0020-7101(79)90015-1.

Abstract

This paper describes the use of a programmable calculator (HP-97), for fitting plasma concentration profiles to 1 and 2 compartment open models and calculating fitted and derived parameters together with estimates of steady state plasma drug levels following various dosage regimens in clinical settings.

摘要

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