Matthew H, Proudfoot A T, Aitken R C, Raeburn J A, Wright N
Br Med J. 1969 Jul 5;3(5661):23-5. doi: 10.1136/bmj.3.5661.23.
In 27 patients nitrazepam (Mogadon) taken in acute overdosage produced no untoward effects except drowsiness, even when 80 tablets were consumed. A double-blind trial in patients in general medical wards established that nitrazepam was as effective as butobarbitone as a hypnotic. It is concluded that nitrazepam is a safe and effective hypnotic.
27名患者急性过量服用硝西泮(硝基安定)后,除嗜睡外未产生其他不良反应,即便服用了80片。在普通内科病房患者中进行的一项双盲试验证实,硝西泮作为催眠药与布他比妥效果相当。结论是硝西泮是一种安全有效的催眠药。