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Enlarged livers and spleens in an area endemic for malaria and schistosomiasis.

作者信息

Whittle H, Gelfand M, Sampson E, Purvis A, Weber M

出版信息

Trans R Soc Trop Med Hyg. 1969;63(3):353-61. doi: 10.1016/0035-9203(69)90010-8.

DOI:10.1016/0035-9203(69)90010-8
PMID:4893920
Abstract
摘要

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Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni.
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Hepatosplenomegaly is associated with low regulatory and Th2 responses to schistosome antigens in childhood schistosomiasis and malaria coinfection.肝脾肿大与儿童血吸虫病和疟疾合并感染时对血吸虫抗原的低调节性和Th2反应相关。
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Micro-geographical variation in exposure to Schistosoma mansoni and malaria, and exacerbation of splenomegaly in Kenyan school-aged children.肯尼亚学龄儿童曼氏血吸虫和疟疾暴露的微观地理差异以及脾肿大的加重情况
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