Datta N
Lancet. 1975 Jun 21;1(7921):1355-7. doi: 10.1016/s0140-6736(75)92262-x.
During a period of 10 weeks, four patients in one hospital became infected with gentamicin-resistant Proteus mirabilis. In two of them septicaemia associated with indwelling catheters developed, one had urinary tract and wound infections, and in the fourth patient the organism was isolated from a superficial wound. The P. mirabilis strains showed multiple drug resistance. Strains form the first three patients were apparently identical and were sensitive to tobramycin. Their gentamicin resistance was not transferable to Escherichia coli K12, but could be transferred to another strain of P. mirablilis (PM13-3). The fourth strain was resistant to tobramycin; its gentamicin/tobramycin resistance was transferable to E. coli K12.
在10周的时间里，一家医院的4名患者感染了对庆大霉素耐药的奇异变形杆菌。其中2人发生了与留置导管相关的败血症，1人有尿路感染和伤口感染，第4名患者的该病菌是从一个浅表伤口分离出来的。这些奇异变形杆菌菌株表现出多重耐药性。前三例患者的菌株明显相同，且对妥布霉素敏感。它们对庆大霉素的耐药性不能转移到大肠杆菌K12，但可以转移到另一株奇异变形杆菌（PM13 - 3）。第四株菌株对妥布霉素耐药；其对庆大霉素/妥布霉素的耐药性可转移到大肠杆菌K12。
