细胞黏菌形态发生过程中的转移RNA甲基化酶
Transfer RNA methylases during morphogenesis in the cellular slime mold.
作者信息
Pillinger D, Borek E
出版信息
Proc Natl Acad Sci U S A. 1969 Apr;62(4):1145-50. doi: 10.1073/pnas.62.4.1145.
Abstract
The enzymes that methylate tRNA were studied during the life cycle of the colonizing slime mold, Dictyostelium discoideum. Total and base specific tRNA methylase activities were determined in extracts from cells in morphogenetic synchrony. Eight hours after enforced aggregation, the total methylase capacity is reduced by about 40 per cent. The diminution appears to be due to the presence of inhibitors that do not inhibit the base specific enzymes to the same extent. There is a still greater diminution in enzyme activity in extracts of the mature fruiting bodies.
摘要
在定殖黏菌盘基网柄菌的生命周期中，对使转运核糖核酸（tRNA）甲基化的酶进行了研究。在形态发生同步的细胞提取物中测定了总tRNA甲基化酶活性和碱基特异性tRNA甲基化酶活性。强制聚集8小时后，总甲基化酶活性降低了约40%。这种降低似乎是由于存在抑制剂，这些抑制剂对碱基特异性酶的抑制程度不同。在成熟子实体的提取物中，酶活性的降低更为明显。
相似文献
1
Transfer RNA methylases during morphogenesis in the cellular slime mold.细胞黏菌形态发生过程中的转移RNA甲基化酶
Proc Natl Acad Sci U S A. 1969 Apr;62(4):1145-50. doi: 10.1073/pnas.62.4.1145.
2
Inhibitor of transfer ribonucleic acid methylase in the differentiating slime mold Dictyostelium discoideum.盘基网柄菌分化过程中转运核糖核酸甲基化酶的抑制剂。
J Bacteriol. 1970 Mar;101(3):705-8. doi: 10.1128/jb.101.3.705-708.1970.
3
Regulation of the tRNA methylases.转运RNA甲基化酶的调控
Fed Proc. 1971 Jan-Feb;30(1):167-76.
4
Synchrony of enzyme accumulation in a population of differentiating slime mold cells.在一群正在分化的黏菌细胞中酶积累的同步性。
Biochim Biophys Acta. 1969 May 6;177(3):610-4. doi: 10.1016/0304-4165(69)90326-2.
5
Activities of glycolytic enzymes during the early stages of differentiation in the cellular slime mold Dictyostelium discoideum.细胞黏菌盘基网柄菌分化早期糖酵解酶的活性
Biochim Biophys Acta. 1968 Feb 1;156(1):44-50. doi: 10.1016/0304-4165(68)90102-5.
6
Dedifferentiation of the disaggregated slug cell of the cellular slime mold Dictyostelium discoideum.盘基网柄菌细胞性黏菌解体的蛞蝓细胞去分化。
Dev Growth Differ. 1971 Dec;13(4):201-10. doi: 10.1111/j.1440-169x.1971.00201.x.
7
8
Inhibition by actinomycin D of uridine diphosphoglucose synthetase activity during differentiation of Dictyostelium discoideum.放线菌素D对盘基网柄菌分化过程中尿苷二磷酸葡萄糖合成酶活性的抑制作用。
J Bacteriol. 1967 Jun;93(6):1762-4. doi: 10.1128/jb.93.6.1762-1764.1967.
9
Inorganic polyphosphates and enzymes of polyphosphate metabolism in the cellular slime mold Dictyostelium discoideum.盘基网柄菌中无机多聚磷酸盐及多聚磷酸盐代谢的酶类
Arch Microbiol. 1974 Jul 22;98(4):311-29. doi: 10.1007/BF00425292.
10
Alteration in timing of cell differentiation resulting from cell interactions during development of the cellular slime mold, Dictyostelium discoideum.在细胞黏菌盘基网柄菌发育过程中，细胞间相互作用导致细胞分化时间的改变。
Dev Biol. 1976 Jun;50(2):489-501. doi: 10.1016/0012-1606(76)90167-6.
引用本文的文献
1
Non-coordinate synthesis and methylation of tRNA following excision of plant tissue.植物组织切除后 tRNA 的非协调合成和甲基化。
Planta. 1973 Sep;114(3):227-38. doi: 10.1007/BF00389038.
2
Properties of the transfer ribonucleic acid methylase activity in vitro of hamster tumours induced by adenovirus-12. Base analysis.腺病毒12诱导的仓鼠肿瘤体外转移核糖核酸甲基酶活性的特性。碱基分析。
Biochem J. 1970 Dec;120(3):499-503. doi: 10.1042/bj1200499.
3
Inhibitor of transfer ribonucleic acid methylase in the differentiating slime mold Dictyostelium discoideum.盘基网柄菌分化过程中转运核糖核酸甲基化酶的抑制剂。
J Bacteriol. 1970 Mar;101(3):705-8. doi: 10.1128/jb.101.3.705-708.1970.
4
Transfer ribonucleic acid methylases during the germination of Neurospora crassa.粗糙脉孢菌萌发过程中的转移核糖核酸甲基化酶
J Bacteriol. 1971 Oct;108(1):446-50. doi: 10.1128/jb.108.1.446-450.1971.
5
Methylation and aging in Rhizoctonia solani.立枯丝核菌中的甲基化与衰老
Mycopathologia. 1976 Dec 10;60(1):57-62. doi: 10.1007/BF00442549.
6
Further investigation of the biosynthesis of caffeine in tea plants (Camellia sinensis L.). Methylation of transfer ribonucleic acid by tea leaf extracts.茶树（Camellia sinensis L.）中咖啡因生物合成的进一步研究。茶叶提取物对转移核糖核酸的甲基化作用。
Biochem J. 1976 Nov 15;160(2):181-4. doi: 10.1042/bj1600181.
本文引用的文献
1
Inhibition of ribonucleic acid methylation in the foot-and-mouth disease virus-infected host cell.
Biochem Biophys Res Commun. 1967 Nov 30;29(4):483-9. doi: 10.1016/0006-291x(67)90509-8.
2
A GENERAL PROCEDURE FOR THE ISOLATION OF "MINOR" NUCLEOSIDES FROM RIBONUCLEIC ACID HYDROLYSATES.从核糖核酸水解物中分离“次要”核苷的一般方法。
Biochemistry. 1965 Apr;4:661-70. doi: 10.1021/bi00880a008.
3
4
A ROLE FOR METHYLATED BASES IN THE AMINO ACID ACCEPTOR FUNCTION OF SOLUBLE RIBONUCLEIC ACID.甲基化碱基在可溶性核糖核酸的氨基酸接受功能中的作用
Proc Natl Acad Sci U S A. 1964 Nov;52(5):1233-8. doi: 10.1073/pnas.52.5.1233.
5
Studies on microbial ribonucleic acid. IV. Two mutants of Saccharomyces cerevisiae lacking N-2-dimethylguanine in soluble ribonucleic acid.微生物核糖核酸的研究。IV。酿酒酵母的两个突变体，其可溶性核糖核酸中缺乏N-2-二甲基鸟嘌呤。
J Mol Biol. 1967 Jun 28;26(3):509-18. doi: 10.1016/0022-2836(67)90318-x.
6
Inhibition of tRNA methylases in lysogenic organisms after induction by ultraviolet irradiation or by heat.紫外线照射或加热诱导后，溶原性生物中tRNA甲基化酶的抑制作用。
J Mol Biol. 1966 Dec 28;22(2):349-53. doi: 10.1016/0022-2836(66)90137-9.
7
Studies on methionyl-tRNA synthetase. 3. Enzyme dependence for maximum methionyl-tRNA formation.甲硫氨酰 - tRNA合成酶的研究。3. 最大程度形成甲硫氨酰 - tRNA对酶的依赖性。
Biochim Biophys Acta. 1968 Aug 27;167(1):179-83. doi: 10.1016/0005-2744(68)90288-x.
8
Restoration of aminoacylation activity of undermethylated transfer RNA by in vitro methylation.通过体外甲基化恢复低甲基化转移RNA的氨酰化活性。
Biochem Biophys Res Commun. 1968 May 10;31(3):404-9. doi: 10.1016/0006-291x(68)90490-7.
9
Methylation of RNA in bacteriophage T4 infected Escherichia coli.
Biochem Biophys Res Commun. 1967 Nov 17;29(3):281-7. doi: 10.1016/0006-291x(67)90449-4.
10
Properties of soluble ribonucleic acid methylases from rat liver.大鼠肝脏可溶性核糖核酸甲基化酶的特性
Biochemistry. 1967 Feb;6(2):451-60. doi: 10.1021/bi00854a013.
Zotero 插件