Eddy N B, Friebel H, Hahn K J, Halbach H
Bull World Health Organ. 1969;40(1):1-53.
This report-the second of a series on codeine and its alternates for pain and cough relief-contains a detailed evaluation of experimental and clinical data on newer substances having analgesic properties comparable to and in approximately the same range as those of codeine. The data are discussed under the headings: analgesic effects in animals; clinical usefulness; side-effects with particular reference to dependence and abuse liability.
本报告——关于可待因及其用于止痛和止咳的替代药物系列报告中的第二篇——详细评估了新型物质的实验和临床数据,这些物质具有与可待因相当且镇痛范围大致相同的镇痛特性。数据按以下标题进行讨论:对动物的镇痛效果;临床效用;副作用,尤其涉及依赖性和滥用可能性。