可待因及其用于缓解疼痛和咳嗽的替代药物。5. 讨论与总结。
Codeine and its alternates for pain and cough relief. 5. Discussion and summary.
作者信息
Eddy N B, Friebel H, Hahn K J, Halbach H
出版信息
Bull World Health Organ. 1969;40(5):721-30.
Abstract
This chapter concludes the survey of experimental and clinical data on the analgesic and antitussive properties of codeine and its potential therapeutic alternates. From an evaluation of their effectiveness on the one hand and the side-effects, including tolerance, dependence and abuse liability on the other, it would appear that the therapeutic goals of codeine could be achieved by other substances, except perhaps where analgesia, cough relief, and sedation are required simultaneously. The use of these other substances would, however, result in no particular gain and probably no particular loss.
摘要
本章总结了关于可待因及其潜在治疗替代物的镇痛和镇咳特性的实验及临床数据调查。一方面从对它们有效性的评估，另一方面从副作用，包括耐受性、依赖性和滥用倾向来看，似乎除了可能需要同时具备镇痛、止咳和镇静作用的情况外，可待因的治疗目标可以通过其他物质实现。然而，使用这些其他物质不会带来特别的益处，可能也不会有特别的损失。
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