Eddy N B, Friebel H, Hahn K J, Halbach H
Bull World Health Organ. 1969;40(3):425-54.
This report-the third of a series on codeine and its alternates for pain and cough relief-presents a detailed review of the physiology and pathophysiology of cough, the methods for the experimental and clinical measurement of the antitussive action of drugs, possible mechanisms of action of antitussive agents, and includes a compilation of experimental results and clinical experience with codeine as an antitussive.
本报告是关于可待因及其用于止痛和止咳替代药物系列报告中的第三篇,详细综述了咳嗽的生理学和病理生理学、药物镇咳作用的实验和临床测量方法、镇咳药可能的作用机制,并汇编了可待因作为镇咳药的实验结果和临床经验。