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相似文献

1
Origin and direction of DNA synthesis in E. coli B-r.大肠杆菌B-r中DNA合成的起源与方向
Proc Natl Acad Sci U S A. 1969 Mar;62(3):881-6. doi: 10.1073/pnas.62.3.881.
2
The replication of the Escherichia coli chromosome studied by sequential nitrosoguanidine mutagenesis.通过连续亚硝基胍诱变研究大肠杆菌染色体的复制。
Cold Spring Harb Symp Quant Biol. 1968;33:599-607. doi: 10.1101/sqb.1968.033.01.066.
3
Control of initiation of DNA synthesis in Escherichia coli B-r.大肠杆菌B-r中DNA合成起始的控制
Proc Natl Acad Sci U S A. 1970 Sep;67(1):255-62. doi: 10.1073/pnas.67.1.255.
4
Synchronous reinitiation of chromosome replication in E. coli B-r after nalidixic acid treatment.萘啶酸处理后大肠杆菌B-r中染色体复制的同步重新起始
Proc Natl Acad Sci U S A. 1970 Jun;66(2):365-9. doi: 10.1073/pnas.66.2.365.
5
Mutagenesis of the replication point by nitrosoguanidine: map and pattern of replication of the Escherichia coli chromosome.用亚硝基胍对复制起点进行诱变：大肠杆菌染色体的复制图谱和模式
J Mol Biol. 1968 May 14;33(3):705-19. doi: 10.1016/0022-2836(68)90315-x.
6
Repair of DNA damaged by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.大肠杆菌中由N-甲基-N'-硝基-N-亚硝基胍损伤的DNA修复
Mutat Res. 1967 May-Jun;4(3):369-71. doi: 10.1016/0027-5107(67)90031-0.
7
[On the mechanism of action of 1-nitroso-3-nitro-1-methylguanidine (NNMG) with respect to mutagenesis. 3. On the inhibition of nucleic acid synthesis and cell-free protein biosynthesis by NNMG and the appearance of resistant Escherichia coli cells after treatment with NNMG].[关于1-亚硝基-3-硝基-1-甲基胍（NNMG）的诱变作用机制。3. NNMG对核酸合成和无细胞蛋白质生物合成的抑制作用以及用NNMG处理后抗性大肠杆菌细胞的出现]
Z Naturforsch B. 1969 Jun;24(6):707-12.
8
Single-strand breaks in Escherichia coli DNA caused by treatment with nitrosoguanidine.亚硝基胍处理导致大肠杆菌DNA中的单链断裂。
Biochim Biophys Acta. 1969 Apr 22;179(2):513-4. doi: 10.1016/0005-2787(69)90063-x.
9
Evidence for multiple growing points on the genome of rapidly growing E. coli B-r.快速生长的大肠杆菌B-r基因组上多个生长点的证据。
Proc Natl Acad Sci U S A. 1969 Jul;63(3):800-4. doi: 10.1073/pnas.63.3.800.
10
Nonrandom mutagenesis of the Escherichia coli genome by nitrosoguanidine.亚硝基胍对大肠杆菌基因组的非随机诱变
J Bacteriol. 1969 May;98(2):847-8. doi: 10.1128/jb.98.2.847-848.1969.

引用本文的文献

1
Localization of a portion of the ribosomal RNA genes in Escherichia coli.大肠杆菌中核糖体RNA基因一部分的定位
Proc Natl Acad Sci U S A. 1971 May;68(5):925-9. doi: 10.1073/pnas.68.5.925.
2
Correlation between rate of cell growth and rate of DNA synthesis in Escherichia coli B-r.大肠杆菌B-r中细胞生长速率与DNA合成速率之间的相关性。
Proc Natl Acad Sci U S A. 1971 May;68(5):1061-4. doi: 10.1073/pnas.68.5.1061.
3
Control of initiation of DNA synthesis in Escherichia coli B-r.大肠杆菌B-r中DNA合成起始的控制
Proc Natl Acad Sci U S A. 1970 Sep;67(1):255-62. doi: 10.1073/pnas.67.1.255.
4
Synchronous reinitiation of chromosome replication in E. coli B-r after nalidixic acid treatment.萘啶酸处理后大肠杆菌B-r中染色体复制的同步重新起始
Proc Natl Acad Sci U S A. 1970 Jun;66(2):365-9. doi: 10.1073/pnas.66.2.365.
5
Sequence of genes replicated in Salmonella typhimurium as examined by transduction techniques.用转导技术检测鼠伤寒沙门氏菌中复制的基因序列。
J Bacteriol. 1970 May;102(2):320-33. doi: 10.1128/jb.102.2.320-333.1970.
6
Requirement of polyamines for bacterial division.细菌分裂对多胺的需求。
J Bacteriol. 1970 Mar;101(3):770-6. doi: 10.1128/jb.101.3.770-776.1970.
7
Analysis of the chloramphenicol-sensitive and chloramphenicol-resistant steps in the initiation of DNA synthesis in E. coli B-r.大肠杆菌B-r中DNA合成起始过程中氯霉素敏感和耐药步骤的分析。
Proc Natl Acad Sci U S A. 1969 Nov;64(3):905-12. doi: 10.1073/pnas.64.3.905.
8
Bi-directional chromosomal replication in Salmonella typhimurium.鼠伤寒沙门氏菌中的双向染色体复制。
J Bacteriol. 1973 Jul;115(1):168-76. doi: 10.1128/jb.115.1.168-176.1973.
9
Metal ion content of Escherichia coli versus cell age.大肠杆菌的金属离子含量与细胞年龄的关系
J Bacteriol. 1976 Jun;126(3):1089-95. doi: 10.1128/jb.126.3.1089-1095.1976.

本文引用的文献

1
THE REPLICATION OF DNA IN ESCHERICHIA COLI.大肠杆菌中DNA的复制
Proc Natl Acad Sci U S A. 1958 Jul 15;44(7):671-82. doi: 10.1073/pnas.44.7.671.
2
ON THE GROWTH MECHANISM OF THE BACTERIAL CHROMOSOME.论细菌染色体的生长机制。
J Mol Biol. 1963 Nov;7:534-40. doi: 10.1016/s0022-2836(63)80100-x.
3
BACTERIAL SYNCHRONIZATION BY SELECTION OF CELLS AT DIVISION.通过在细胞分裂时进行选择实现细菌同步化
Proc Natl Acad Sci U S A. 1963 Oct;50(4):767-74. doi: 10.1073/pnas.50.4.767.
4
THE EFFECT OF AMINO ACID DEPRIVATION ON SUBSEQUENT DEOXYRIBONUCLEIC ACID REPLICATION.氨基酸剥夺对后续脱氧核糖核酸复制的影响。
Biochim Biophys Acta. 1963 Sep 17;76:9-24.
5
The bacterial chromosome and its manner of replication as seen by autoradiography.通过放射自显影观察到的细菌染色体及其复制方式。
J Mol Biol. 1963 Mar;6:208-13. doi: 10.1016/s0022-2836(63)80070-4.
6
The molecular synchrony and sequential replication of DNA in Escherichia coli.大肠杆菌中DNA的分子同步性和序列复制
Proc Natl Acad Sci U S A. 1963 Apr;49(4):551-9. doi: 10.1073/pnas.49.4.551.
7
Transduction of linked genetic characters of the host by bacteriophage P1.噬菌体P1对宿主连锁遗传性状的转导
Virology. 1955 Jul;1(2):190-206. doi: 10.1016/0042-6822(55)90016-7.
8
Beta-galactosidase formation controlled by an episomal gene during the cell cycle of Escherichia coli.在大肠杆菌细胞周期中，由附加体基因控制的β-半乳糖苷酶形成。
J Biochem. 1966 Sep;60(3):338-40. doi: 10.1093/oxfordjournals.jbchem.a128442.
9
Inversion of transfer modes and sex factor-chromosome interactions in conjugation in Escherichia coli.大肠杆菌接合过程中转移模式的反转以及性因子与染色体的相互作用
J Bacteriol. 1967 Jan;93(1):98-106. doi: 10.1128/jb.93.1.98-106.1967.
10
Evidence for polarity of chromosome replication in F- strains of Escherichia coli.大肠杆菌F-菌株中染色体复制极性的证据。
Genet Res. 1966 Aug;8(1):119-24. doi: 10.1017/s0016672300009976.

大肠杆菌B-r中DNA合成的起源与方向

Origin and direction of DNA synthesis in E. coli B-r.

作者信息

Ward C B, Glaser D A

出版信息

Proc Natl Acad Sci U S A. 1969 Mar;62(3):881-6. doi: 10.1073/pnas.62.3.881.

DOI:10.1073/pnas.62.3.881
PMID:4895216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC223680/
Abstract

Replication of the chromosome of E. coli B/r has been studied by measuring the change with cell age of the rates of reversion to wild type of auxotrophic markers induced by nitrosoguanidine. Synchronous populations of bacteria were obtained by the procedure of Helmstetter and Cummings. The origin of DNA synthesis was determined to occur at 49 minutes +/- 5 minutes on the genetic map, and the direction of synthesis was found to be clockwise.

摘要

通过测量亚硝基胍诱导的营养缺陷型标记回复为野生型的速率随细胞年龄的变化，对大肠杆菌B/r染色体的复制进行了研究。通过Helmstetter和Cummings的方法获得了细菌同步群体。确定DNA合成起点在遗传图谱上49分钟±5分钟处，且合成方向为顺时针。