• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Endonuclease II of E. coli. I. Isolation and purification.大肠杆菌核酸内切酶II。I. 分离与纯化。
Proc Natl Acad Sci U S A. 1969 Mar;62(3):934-40. doi: 10.1073/pnas.62.3.934.
2
An endonuclease for depurinated DNA in rat liver.大鼠肝脏中一种作用于脱嘌呤DNA的核酸内切酶。
Can J Biochem. 1973 Jul;51(7):1003-9. doi: 10.1139/o73-130.
3
Endonuclease II of E. coli.大肠杆菌核酸内切酶II
Cold Spring Harb Symp Quant Biol. 1968;33:271-5. doi: 10.1101/sqb.1968.033.01.031.
4
Some findings on the endonuclease of pneumococci.关于肺炎球菌核酸内切酶的一些发现。
Folia Microbiol (Praha). 1969;14(1):54-61. doi: 10.1007/BF02869400.
5
[A new method of isolation and purification of SsoII restriction endonuclease].
Biokhimiia. 1993 Jun;58(6):908-12.
6
An endonuclease for depurinated DNA in Escherichia coli B.大肠杆菌B中用于脱嘌呤DNA的核酸内切酶。
Can J Biochem. 1972 Feb;50(2):217-24. doi: 10.1139/o72-029.
7
Endonuclease II, apurinic acid endonuclease, and exonuclease III.核酸内切酶II、脱嘌呤酸核酸内切酶和核酸外切酶III。
Proc Natl Acad Sci U S A. 1976 Dec;73(12):4324-8. doi: 10.1073/pnas.73.12.4324.
8
Studies on deoxyribonucleases from Saccharomyces cerevisiae. Characterization of two endonuclease activities with a preference for double-stranded DNA.酿酒酵母中脱氧核糖核酸酶的研究。对两种偏好双链DNA的内切核酸酶活性的表征。
Nucleic Acids Res. 1975 Jul;2(7):1023-42. doi: 10.1093/nar/2.7.1023.
9
An endonuclease activity from Escherichia coli absent from certain rec- strains.来自大肠杆菌的一种核酸内切酶活性,某些rec-菌株中不存在该活性。
Proc Natl Acad Sci U S A. 1970 Sep;67(1):434-41. doi: 10.1073/pnas.67.1.434.
10
Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis.通过有限蛋白酶解选择性去除大肠杆菌B中脱氧核糖核酸聚合酶的核酸外切酶活性。
Proc Natl Acad Sci U S A. 1970 Jan;65(1):168-75. doi: 10.1073/pnas.65.1.168.

引用本文的文献

1
Master molecule, heal thyself.主导分子,自我修复。
J Biol Chem. 2014 May 16;289(20):13691-700. doi: 10.1074/jbc.X114.572115. Epub 2014 Apr 7.
2
T4 endonuclease involved in repair of DNA.参与DNA修复的T4核酸内切酶。
Proc Natl Acad Sci U S A. 1970 Dec;67(4):1839-45. doi: 10.1073/pnas.67.4.1839.
3
Repair of alkylation damage: stability of methyl groups in Bacillus subtilis treated with methyl methanesulfonate.烷基化损伤的修复:用甲磺酸甲酯处理的枯草芽孢杆菌中甲基的稳定性
J Bacteriol. 1970 Jun;102(3):760-6. doi: 10.1128/jb.102.3.760-766.1970.
4
Sensitivity of intracellular bacteriophage lambda to colicin CA42-E2.细胞内噬菌体λ对大肠杆菌素CA42-E2的敏感性
J Virol. 1971 Oct;8(4):355-62. doi: 10.1128/JVI.8.4.355-362.1971.
5
Excision of damaged thymine residues from gamma-irradiated poly(dA-dT) by crude extracts of Escherichia coli.利用大肠杆菌粗提取物从γ射线辐照的聚(dA-dT)中切除受损胸腺嘧啶残基
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3532-6. doi: 10.1073/pnas.71.9.3532.
6
The enzymatic release of O6-methylguanine and 3-methyladenine from DNA reacted with the carcinogen N-methyl-N-nitrosourea.与致癌物N-甲基-N-亚硝基脲反应的DNA中O6-甲基鸟嘌呤和3-甲基腺嘌呤的酶促释放。
Proc Natl Acad Sci U S A. 1974 May;71(5):2022-6. doi: 10.1073/pnas.71.5.2022.
7
Mutations simultaneously affecting endonuclease II and exonuclease III in Escherichia coli.大肠杆菌中同时影响内切核酸酶II和外切核酸酶III的突变
Proc Natl Acad Sci U S A. 1975 Feb;72(2):688-92. doi: 10.1073/pnas.72.2.688.
8
Enzymatic degradation of uracil-containing DNA. II. Evidence for N-glycosidase and nuclease activities in unfractionated extracts of Bacillus subtilis.含尿嘧啶DNA的酶促降解。II. 枯草芽孢杆菌未分级提取物中N-糖苷酶和核酸酶活性的证据。
J Virol. 1976 Aug;19(2):338-45. doi: 10.1128/JVI.19.2.338-345.1976.
9
Endonuclease II, apurinic acid endonuclease, and exonuclease III.核酸内切酶II、脱嘌呤酸核酸内切酶和核酸外切酶III。
Proc Natl Acad Sci U S A. 1976 Dec;73(12):4324-8. doi: 10.1073/pnas.73.12.4324.
10
Mechanism of the radioprotecting action of chemical compounds on Escherichia coli cells.化合物对大肠杆菌细胞的辐射防护作用机制。
Mol Gen Genet. 1978 Jul 6;163(1):75-85. doi: 10.1007/BF00268966.

本文引用的文献

1
The deoxyribonucleases of Escherichia coli. II. Purification and properties of a ribonucleic acid-inhibitable endonuclease.大肠杆菌的脱氧核糖核酸酶。II. 一种核糖核酸抑制性内切核酸酶的纯化及特性
J Biol Chem. 1962 Mar;237:819-28.
2
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.DNA大小与形状的沉降研究
J Mol Biol. 1965 Feb;11:373-90. doi: 10.1016/s0022-2836(65)80064-x.
3
THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. V. ON THE SPECIFICITY OF EXONUCLEASE I (PHOSPHODIESTERASE).大肠杆菌的脱氧核糖核酸酶。V. 关于核酸外切酶I(磷酸二酯酶)的特异性
J Biol Chem. 1964 Aug;239:2628-36.
4
A DEOXYRIBONUCLEIC ACID PHOSPHATASE-EXONUCLEASE FROM ESCHERICHIA COLI. I. PURIFICATION OF THE ENZYME AND CHARACTERIZATION OF THE PHOSPHATASE ACTIVITY.来自大肠杆菌的一种脱氧核糖核酸磷酸酶-核酸外切酶。I. 酶的纯化及磷酸酶活性的表征
J Biol Chem. 1964 Jan;239:242-50.
5
THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE.大肠杆菌的脱氧核糖核酸酶。IV. 脱氧核糖核酸聚合酶纯化制剂中存在的一种核酸外切酶活性
J Biol Chem. 1964 Jan;239:233-41.
6
Rapid method for determining the activity of microorganisms on nucleic acids.用于测定微生物对核酸活性的快速方法。
J Bacteriol. 1957 Apr;73(4):590-1. doi: 10.1128/jb.73.4.590-591.1957.
7
The deoxyribonucleases of Escherichia coli. VII. A deoxyribonuclease induced by infection with phage T-5.
J Biol Chem. 1966 Jul 25;241(14):3441-51.
8
Effects of some chemical mutagens and carcinogens on nucleic acids.某些化学诱变剂和致癌物对核酸的影响。
Prog Nucleic Acid Res Mol Biol. 1966;5:89-131. doi: 10.1016/s0079-6603(08)60232-9.
9
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.DNA链生长的机制。I. 新合成链可能的不连续性和异常二级结构。
Proc Natl Acad Sci U S A. 1968 Feb;59(2):598-605. doi: 10.1073/pnas.59.2.598.
10
Localization of E. coli endonuclease I.大肠杆菌核酸内切酶I的定位
Biochem Biophys Res Commun. 1965 Sep 8;20(5):555-9. doi: 10.1016/0006-291x(65)90434-1.

大肠杆菌核酸内切酶II。I. 分离与纯化。

Endonuclease II of E. coli. I. Isolation and purification.

作者信息

Friedberg E C, Goldthwait D A

出版信息

Proc Natl Acad Sci U S A. 1969 Mar;62(3):934-40. doi: 10.1073/pnas.62.3.934.

DOI:10.1073/pnas.62.3.934
PMID:4895219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC223688/
Abstract

The isolation and purification of a new endonuclease of E. coli is described. This enzyme degrades alkylated DNA as assayed by a technique that requires double-strand scission. The enzyme also makes a limited number of single-strand breaks in native nonalkylated DNA.

摘要

本文描述了从大肠杆菌中分离和纯化一种新的核酸内切酶的过程。通过一种需要双链断裂的技术检测发现,这种酶能降解烷基化的DNA。该酶还会在天然的非烷基化DNA中产生有限数量的单链断裂。