Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.
作者信息
Okazaki R, Okazaki T, Sakabe K, Sugimoto K, Sugino A
出版信息
Proc Natl Acad Sci U S A. 1968 Feb;59(2):598-605. doi: 10.1073/pnas.59.2.598.
Abstract
摘要
相似文献
1
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.DNA链生长的机制。I. 新合成链可能的不连续性和异常二级结构。
Proc Natl Acad Sci U S A. 1968 Feb;59(2):598-605. doi: 10.1073/pnas.59.2.598.
2
Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation.紫外线照射后，大肠杆菌切除缺陷菌株中合成的DNA的不连续性。
J Mol Biol. 1968 Jan 28;31(2):291-304. doi: 10.1016/0022-2836(68)90445-2.
3
Discontinuous synthesis of DNA during replication.复制过程中DNA的不连续合成。
Proc Natl Acad Sci U S A. 1968 Nov;61(3):1129-36. doi: 10.1073/pnas.61.3.1129.
4
Deoxyribonucleic acid secondary structure in the region of the replication point.复制点区域的脱氧核糖核酸二级结构
J Mol Biol. 1966 May;17(1):1-9. doi: 10.1016/s0022-2836(66)80089-x.
5
The conversion of viral heads to T5 phage in vivo.病毒头部在体内转化为T5噬菌体。
J Gen Virol. 1968 Dec;3(3):459-63. doi: 10.1099/0022-1317-3-3-459.
6
Mechanism of DNA chain growth. IV. Direction of synthesis of T4 short DNA chains as revealed by exonucleolytic degradation.DNA链生长的机制。IV。通过核酸外切酶降解揭示的T4短DNA链的合成方向。
Proc Natl Acad Sci U S A. 1969 Dec;64(4):1242-8. doi: 10.1073/pnas.64.4.1242.
7
Studies of DNA replication in vivo. I. Isolation of the first intermediate of DNA replication in bacteria as single-stranded DNA.体内DNA复制的研究。I. 细菌中DNA复制首个中间体作为单链DNA的分离。
Proc Natl Acad Sci U S A. 1968 May;60(1):329-36. doi: 10.1073/pnas.60.1.329.
8
Persistence of small fragments of newly synthesized DNA in bacteria following thymidine starvation.胸苷饥饿后细菌中新合成DNA小片段的持久性。
J Mol Biol. 1971 Apr 28;57(2):351-4. doi: 10.1016/0022-2836(71)90351-2.
9
Asymmetric segregation of the complementary sex-factor DNA strands during conjugation in Escherichia coli.大肠杆菌接合过程中互补性因子DNA链的不对称分离。
J Mol Biol. 1970 Nov 14;53(3):287-303. doi: 10.1016/0022-2836(70)90066-5.
10
Mechanism of DNA chain growth, II. Accumulation of newly synthesized short chains in E. coli infected with ligase-defective T4 phages.DNA链生长机制，II。在感染连接酶缺陷型T4噬菌体的大肠杆菌中新合成短链的积累。
Proc Natl Acad Sci U S A. 1968 Aug;60(4):1356-62. doi: 10.1073/pnas.60.4.1356.
引用本文的文献
1
DragonRNA: Generality of DNA-primed RNA-extension activities by DNA-directed RNA polymerases.龙RNA：DNA指导的RNA聚合酶引发的DNA引发的RNA延伸活性的普遍性
Nucleic Acids Res. 2025 Mar 20;53(6). doi: 10.1093/nar/gkaf236.
2
CDK-mediated phosphorylation of PNKP is required for end-processing of single-strand DNA gaps on Okazaki fragments and genome stability.CDK介导的PNKP磷酸化是冈崎片段上单链DNA缺口的末端加工和基因组稳定性所必需的。
Elife. 2025 Mar 27;14:e99217. doi: 10.7554/eLife.99217.
3
- Transcriptional Cascade Suggests Activation Mechanism for -Dependent Alternative Lengthening of Telomeres During Malignant Transformation of Malignant Peripheral Nerve Sheath Tumors: Elongation of Telomeres and Poor Survival.转录级联反应揭示恶性周围神经鞘瘤恶变过程中依赖于端粒酶的端粒替代延长激活机制：端粒延长与不良生存
Biomedicines. 2025 Jan 23;13(2):281. doi: 10.3390/biomedicines13020281.
4
Sequencing and Optical Genome Mapping for the Adventurous Chemist.面向勇于探索的化学家的测序与光学基因组图谱技术。
Chem Biomed Imaging. 2024 Oct 25;2(12):784-807. doi: 10.1021/cbmi.4c00060. eCollection 2024 Dec 23.
5
TGF-β superfamily-induced transcriptional activation pathways establish the RAD52-dependent ALT machinery during malignant transformation of MPNSTs.TGF-β 超家族诱导的转录激活途径在 MPNSTs 的恶性转化过程中建立了依赖 RAD52 的 ALT 机制。
Sci Rep. 2024 Nov 2;14(1):26475. doi: 10.1038/s41598-024-76732-z.
6
An emerging paradigm in epigenetic marking: coordination of transcription and replication.表观遗传标记中的新兴范式：转录和复制的协调。
Transcription. 2024 Feb-Apr;15(1-2):22-37. doi: 10.1080/21541264.2024.2316965. Epub 2024 Feb 20.
7
The Life and Science of Professor Tsuneko Okazaki, and her time at Fujita Health University.冈崎恒子教授的生平与科学成就，以及她在藤田保健大学的时光。
Fujita Med J. 2024 Feb;10(1):1-7. doi: 10.20407/fmj.2023-014. Epub 2023 Nov 29.
8
Genome maintenance meets mechanobiology.基因组维护与机械生物学相遇。
Chromosoma. 2024 Jan;133(1):15-36. doi: 10.1007/s00412-023-00807-5. Epub 2023 Aug 15.
9
Primase-polymerases: how to make a primer from scratch.引物酶聚合酶：从头开始制造引物。
Biosci Rep. 2023 Jul 26;43(7). doi: 10.1042/BSR20221986.
10
Bacillus subtilis encodes a discrete flap endonuclease that cleaves RNA-DNA hybrids.枯草芽孢杆菌编码一种离散的核酸内切酶，可切割 RNA-DNA 杂交体。
PLoS Genet. 2023 May 5;19(5):e1010585. doi: 10.1371/journal.pgen.1010585. eCollection 2023 May.
本文引用的文献
1
The deoxyribonucleases of Escherichia coli. I. Purification and properties of a phosphodiesterase.大肠杆菌的脱氧核糖核酸酶。I. 一种磷酸二酯酶的纯化及性质
J Biol Chem. 1960 May;235:1479-87.
2
NUCLEOTIDE COMPOSITION OF SHORT SEGMENTS OF DNA MOLECULES.DNA分子短片段的核苷酸组成
J Mol Biol. 1965 Feb;11:223-37. doi: 10.1016/s0022-2836(65)80053-5.
3
THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. V. ON THE SPECIFICITY OF EXONUCLEASE I (PHOSPHODIESTERASE).大肠杆菌的脱氧核糖核酸酶。V. 关于核酸外切酶I（磷酸二酯酶）的特异性
J Biol Chem. 1964 Aug;239:2628-36.
4
ON THE GROWTH MECHANISM OF THE BACTERIAL CHROMOSOME.论细菌染色体的生长机制。
J Mol Biol. 1963 Nov;7:534-40. doi: 10.1016/s0022-2836(63)80100-x.
5
Sequential replication of Bacillus subtilis chromosome. I. Comparison of marker frequencies in exponential and stationary growth phases.枯草芽孢杆菌染色体的顺序复制。I. 指数生长期和稳定生长期标记频率的比较。
Proc Natl Acad Sci U S A. 1963 Apr;49(4):559-66. doi: 10.1073/pnas.49.4.559.
6
The molecular synchrony and sequential replication of DNA in Escherichia coli.大肠杆菌中DNA的分子同步性和序列复制
Proc Natl Acad Sci U S A. 1963 Apr;49(4):551-9. doi: 10.1073/pnas.49.4.551.
7
Chromatography of nucleic acids on hydroxyapatite.核酸在羟基磷灰石上的色谱分析。
Nature. 1965 May 22;206(4986):779-83. doi: 10.1038/206779a0.
8
Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli.来自大肠杆菌的一种酶通过磷酸二酯键连接多核苷酸。
Proc Natl Acad Sci U S A. 1967 May;57(5):1426-33. doi: 10.1073/pnas.57.5.1426.
9
Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage.脱氧核糖核酸的酶促断裂与连接，I. 用感染T4噬菌体的大肠杆菌的酶系统修复DNA中的单链断裂
Proc Natl Acad Sci U S A. 1967 Apr;57(4):1021-8. doi: 10.1073/pnas.57.4.1021.
10
A unique property of the replicating region of chromosomal DNA.染色体DNA复制区域的一个独特特性。
Biochim Biophys Acta. 1966 Dec 21;129(3):651-4. doi: 10.1016/0005-2787(66)90088-8.
Zotero 插件