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梅毒螺旋体Nichols株的抗原结构。II. 具有“菌株特异性”血清学活性的多糖抗原的提取。

Antigenic structure of Treponema pallidum, Nichols strain. II. Extraction of a polysaccharide antigen with "strain-specific" serological activity.

作者信息

Miller J N, Bekker J H, DeBruijn J H, Onvlee P C

出版信息

J Bacteriol. 1969 Jul;99(1):132-5. doi: 10.1128/jb.99.1.132-135.1969.

Abstract

An ultracentrifugally homogeneous heat-stable polysaccharide preparation free from serologically reactive rabbit testicular tissue antigen, including cardiolipin, was extracted from the Nichols strain of Treponema pallidum, and found to react by complement-fixation with homologous rabbit sera but not with human syphilitic sera. In addition, the reactive "strain-specific" component was found to be distinct from a second reactive component within the preparation related to an antigen of T. reiteri.

摘要

从梅毒螺旋体 Nichols 菌株中提取出一种超速离心均一、热稳定的多糖制剂,该制剂不含包括心磷脂在内的血清学反应性兔睾丸组织抗原,发现其能与同源兔血清发生补体结合反应,但不能与人梅毒血清发生反应。此外,发现这种反应性“菌株特异性”成分与制剂中与回归热螺旋体抗原相关的第二种反应性成分不同。

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