Martin G F, Humbertson A O, Laxson L C, Panneton W M, Tschismadia I
J Comp Neurol. 1979 Sep 15;187(2):373-99. doi: 10.1002/cne.901870208.
The results from several experimental approaches lead to the following conclusions. The nucleus cuneiformis projects to at least lumbar levels of the spinal cord. Its axons course through the ipsilateral sulcomarginal and ventral funiculi to distribute within lamina VIII and adjacent portions of lamina VII. Neurons within the nucleus reticularis pontis (RP), particularly within more medial parts of the nucleus, project through comparable routes to the same laminae. In addition, however, neurons within the lateral and dorsolateral RP relay through the lateral and dorsolateral funiculi, ipsilaterally, and the dorsolateral funiculus, contralaterally. Axons could be traced from the dorsolateral tracts to laminae IV through VII, lamina X and, in some instances, to laminae I and II. Injections of the dorsolateral pons also label the intermediolateral cell column and an area presumed to be the sacral parasympathetic nucleus. Many of the neurons which contribute to the contralateral bundle are located adjacent to the ventral nucleus of the lateral lemniscus. The nucleus reticularis gigantocellularis projects mainly via the sulcomarginal, ventral and lateral funiculi to laminae VIII and adjacent portions of lamina VII. The nucleus reticularis gigantocellularis pars ventralis innervates the same laminae; but, in addition, projects heavily to laminae I and II, to lateral portions of laminae IV through VII; to laminae IX and X and to the intermediolateral cell column. Axons destined for laminae I and II, as well as IV through VII and X, traverse the dorsolateral funiculi as described for the cat by Basbaum et al. ('78). Neurons within the nucleus reticularis parvocellularis project to cervical levels, mainly through the ventral funiculi. In general our results show that reticulospinal projections are more complex than suggested by degeneration methods and that laminae I, II. lateral parts of laminae IV-VII, laminae IX and X, as well as the intermediolateral cell column and sacral parasympathetic nucleus are targets of axons from specific areas.
几种实验方法所得结果得出以下结论。楔状核投射至脊髓至少腰段水平。其轴突经同侧缘沟和腹侧索走行，分布于板层VIII及板层VII的相邻部分。脑桥网状核（RP）内的神经元，尤其是核内侧部的神经元，经类似路径投射至相同板层。然而，此外，外侧和背外侧RP内的神经元经同侧的外侧和背外侧索以及对侧的背外侧索中继。轴突可从背外侧束追踪至板层IV至VII、板层X，在某些情况下，还可追踪至板层I和II。背外侧脑桥注射也标记中间外侧细胞柱和一个推测为骶副交感核的区域。许多参与对侧束的神经元位于外侧丘系腹侧核附近。巨细胞网状核主要经缘沟、腹侧和外侧索投射至板层VIII及板层VII的相邻部分。巨细胞网状核腹侧部支配相同板层；但此外，还大量投射至板层I和II、板层IV至VII的外侧部分、板层IX和X以及中间外侧细胞柱。如巴斯鲍姆等人（1978年）对猫的描述，去往板层I和II以及IV至VII和X的轴突穿过背外侧索。小细胞网状核内的神经元主要经腹侧索投射至颈段水平。总体而言，我们的结果表明，网状脊髓投射比退变方法所显示的更为复杂，并且板层I、II、板层IV - VII的外侧部分、板层IX和X以及中间外侧细胞柱和骶副交感核是特定区域轴突的靶标。
