Guyer R J, Crowther D
Br Med J. 1969 Nov 15;4(5680):406-7. doi: 10.1136/bmj.4.5680.406.
Active non-specific immunotherapy has been used to prolong remissions in acute lymphoblastic leukaemia. The series reported here used Bordetella pertussis vaccine in a controlle trial after intensive chemotherapy. Possibly immunotherapy delayed the onset of relapse in the treated patients, but no long-term remissions were obtained. Further work is needed to establish the role of immunotherapy in general, and the use of B. pertussis vaccine in particular, in the treatment of acute leukaemia.
活性非特异性免疫疗法已被用于延长急性淋巴细胞白血病的缓解期。本文报道的系列研究在强化化疗后,在一项对照试验中使用了百日咳博德特氏菌疫苗。免疫疗法可能延迟了治疗患者复发的发生,但未获得长期缓解。需要进一步开展工作,以确定免疫疗法总体上,特别是百日咳博德特氏菌疫苗在急性白血病治疗中的作用。