儿童急性淋巴细胞白血病的周期性化疗：5年生存率
Cyclic chemotherapy in acute lymphoblastic leukaemia of childhood: 5-year survivals.
作者信息
Vowels M R, Willoughby M L
出版信息
Arch Dis Child. 1973 Jun;48(6):436-40. doi: 10.1136/adc.48.6.436.
Abstract
Of 31 children with acute lymphoblastic leukaemia treated with a cyclical scheme of chemotherapy, 19% survived for over 5 years, 16% remained in continuing haematological remission for 5 years, and 13% remained leukaemia free for 5 years. These findings are relevant to potential cure, unlike the median remission duration, which is a measure of palliation. A relation between the percentage of PAS-positive blast cells at diagnosis and duration of control of the disease still pertains for the long-term results in this series of patients.
摘要
在采用周期性化疗方案治疗的31例急性淋巴细胞白血病患儿中，19%存活超过5年，16%持续血液学缓解达5年，13%无白血病生存达5年。这些发现与潜在治愈相关，与作为缓解指标的中位缓解持续时间不同。在这组患者的长期结果中，诊断时PAS阳性原始细胞百分比与疾病控制持续时间之间的关系仍然存在。
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